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Showing 1–5 of 5 results
Advanced filters: Author: Amanda Phuong Tran Clear advanced filters

  • Demyelination failure in multiple sclerosis (MS) may contribute to the disease progression. This study shows that chondroitin sulfate proteoglycans (CSPGs) can inhibit remyelination in an animal model of MS via CSPG binding with the receptor PTPσ on oligodendrocyte progenitor cells, and disruption of this interaction can promote recovery in the animal models of MS.

    • Fucheng Luo
    • Amanda Phuong Tran
    • Yan Yang
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16

  • The cell of origin for high-grade serous carcinoma (HGSC) remains to be determined. Here, the authors characterize the different cell types and states of the mouse uterine tube and identify transitional pre-ciliated cells as a cancer-prone cell state, which could be targeted therapeutically.

    • Andrea Flesken-Nikitin
    • Coulter Q. Ralston
    • Alexander Yu. Nikitin
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • This study shows that climate-driven hydrology primarily controls subsurface rock carbon weathering, with the groundwater table regulating the weathering depth and subsurface water fluxes determining the transported forms and rates of carbon released from rocks, based on measurements in the East River watershed, Rocky Mountains, United States.

    • Jiamin Wan
    • Tetsu K. Tokunaga
    • Kenneth H. Williams
    ResearchOpen Access
    Nature Water
    Volume: 2, P: 848-862

  • Fewer than 100 wild Cat Ba langurs survive in Vietnam. Here, the authors use whole genome sequencing to demonstrate potential adaptations to saltwater consumption as well as maintenance of adaptive potential despite low levels of genetic diversity and high levels of inbreeding.

    • Liye Zhang
    • Neahga Leonard
    • Christian Roos
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14