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Showing 1–2 of 2 results
Advanced filters: Author: Amandine Mathias Clear advanced filters

  • Autoimmune encephalitis (AIE) may involve neuron-specific cytotoxic T cells, but evidence is still lacking. Here the authors use induced pluripotent stem cells from patients with AIE and single cell RNA-sequencing of ex vivo CD8 T cells to find neuron-specific, KIR+CD8+ T cells with altered transcriptome that potentially contribute to AIE etiology.

    • Sylvain Perriot
    • Samuel Jones
    • Renaud Du Pasquier
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Encephalitis is a rare and severe complication of Herpes Simplex type 1 infection. Here, Bibert et al describe a genetic variant in a 2-year-old affected child that impairs interferon production in neuronal cells and enhances viral replication.

    • Stéphanie Bibert
    • Mathieu Quinodoz
    • Pierre-Yves Bochud
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14