Genetic variance is vital for breeding programs and mutant screening, yet traditional mutagenesis methods wrestle with genetic redundancy and a lack of specificity in gene targeting. Here the authors develop a scalable CRISPR system in tomato to edit multiple genes at once, overcoming genetic redundancy and revealing new traits related to fruit quality, nutrient use, and disease resistance.
- Amichai Berman
- Ning Su
- Eilon Shani