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Showing 1–3 of 3 results
Advanced filters: Author: Amit Rimon Clear advanced filters

  • Inhibition of PERK, an endoplasmic reticulum (ER) unfolded protein response (UPR) protein, is a potential pharmacological target for cancer treatment. Here, the authors show that inhibition of PERK under ER stress affects trafficking from the ER to the surface of several key receptor tyrosine kinases, suggesting a selective ER retention.

    • Mohamed Mahameed
    • Shatha Boukeileh
    • Boaz Tirosh
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Bacteriophage therapy is evolving as a promising approach to tackling bacterial infection, even in the case of emerging antibiotic resistance. In this work, authors present the topical application of numerous Cutibacterium acnes phage in an in vivo mouse model of acne vulgaris.

    • Amit Rimon
    • Chani Rakov
    • Ronen Hazan
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics.

    • Gal Masrati
    • Manish Dwivedi
    • Nir Ben-Tal
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14