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Advanced filters: Author: Amy C. Mandigo Clear advanced filters

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

Cryptochrome 1 (CRY1) is a transcriptional coregulator associated with the circadian clock. Here the authors reveal that CRY1 is hormone-regulated, stabilized by genomic insult, and promotes DNA repair and cell survival through temporal transcriptional regulation.

Ayesha A. Shafi
Chris M. McNair
Karen E. Knudsen
ResearchOpen Access15 Jan 2021
Nature Communications

Volume: 12, P: 1-15
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes

Jennifer J. McCann
Irina A. Vasilevskaya
Karen E. Knudsen
ResearchOpen Access12 Nov 2021
Oncogene

Volume: 41, P: 444-458

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The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes

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