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Showing 1–5 of 5 results
Advanced filters: Author: Ana Carina Bon-Frauches Clear advanced filters

  • In a mouse model, aryl hydrocarbon receptor signalling in enteric neurons is revealed as a mechanism that helps to maintain gut homeostasis by integrating the luminal environment with the physiology of intestinal neural circuits.

    • Yuuki Obata
    • Álvaro Castaño
    • Vassilis Pachnis
    Research
    Nature
    Volume: 578, P: 284-289

  • Enteric glial cells have tissue-wide immunoregulatory roles through the upregulation of IFNγ-dependent genes both at steady state and after parasite infection, promoting immune homeostasis and CXCL10-mediated tissue repair after pathogen-induced intestinal damage in mice.

    • Fränze Progatzky
    • Michael Shapiro
    • Vassilis Pachnis
    Research
    Nature
    Volume: 599, P: 125-130

  • The enteric nervous system (ENS) is an important component of gastrointestinal function and a pivotal hub connecting the gut to other organs. A new study now explores the human and mouse ENS at the single-cell level, providing key insights into the transcriptomic landscape of the ENS and its constituent cells.

    • Ana Carina Bon-Frauches
    • Werend Boesmans
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 17, P: 717-718

  • Fluorescently labeled nuclei of the enteric nervous system are isolated from adult mouse or zebrafish gut and characterized by nuclear RNA sequencing and visualization and quantification of transcripts using a custom analytical pipeline.

    • Yuuki Obata
    • Álvaro Castaño
    • Vassilis Pachnis
    Protocols
    Nature Protocols
    Volume: 17, P: 1789-1817