It has been shown that planar cell polarity (PCP) signalling and cilium positioning are linked. Montcouquiol and colleagues now show that G-protein signalling, through the GTP-binding G-protein subunit Gαi3 and the apicobasal polarity protein mPins, modulates cilium positioning cell autonomously. They also show that PCP signalling controls cilium positioning at the tissue level.
- Jerome Ezan
- Léa Lasvaux
- Mireille Montcouquiol
