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Showing 1–50 of 65 results

Advanced filters: Author: Ana Parra Clear advanced filters

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

Analyses of neuroimaging datasets from 5,306 participants across 15 countries found generally larger brain-age gaps in Latin American compared with non-Latin American populations, which were influenced by disparities in socioeconomic and health-related factors.

Sebastian Moguilner
Sandra Baez
Agustin Ibanez
ResearchOpen Access26 Aug 2024
Nature Medicine

Volume: 30, P: 3646-3657
Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

Crhistian-Mario Oblitas
Pablo Demelo-Rodríguez
Hector Meijide Míguez
ResearchOpen Access05 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry

José-Manuel Casas-Rojo
Juan-Miguel Antón-Santos
Hector Meijide Míguez
ResearchOpen Access18 Oct 2023
Scientific Reports

Volume: 13, P: 1-18
Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Genotype and exome sequencing of 150,000 participants and whole-genome sequencing of 9,950 selected individuals recruited into the Mexico City Prospective Study constitute a valuable, publicly available resource of non-European sequencing data.

Andrey Ziyatdinov
Jason Torres
Roberto Tapia-Conyer
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 784-793
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Mosquito vector competence for dengue is modulated by insect-specific viruses

From metagenomics of Aedes mosquitoes from four continents, the authors analyse the mechanism by which insect-specific viruses affect mosquito vector competence to transmit dengue virus to humans.

Roenick P. Olmo
Yaovi M. H. Todjro
João T. Marques
Research05 Jan 2023
Nature Microbiology

Volume: 8, P: 135-149
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

A meta-analysis of genome-wide association studies of type 2 diabetes (T2D) identifies more than 600 T2D-associated loci; integrating physiological trait and single-cell chromatin accessibility data at these loci sheds light on heterogeneity within the T2D phenotype.

Ken Suzuki
Konstantinos Hatzikotoulas
Eleftheria Zeggini
ResearchOpen Access19 Feb 2024
Nature

Volume: 627, P: 347-357
The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

Analysis of 2,170 SARS-CoV-2 sequences from the first wave of the COVID-19 epidemic in Spain provides insights into transmission patterns and the effects of lockdown on the emergence of new variants.

Mariana G. López
Álvaro Chiner-Oms
Iñaki Comas
Research30 Sept 2021
Nature Genetics

Volume: 53, P: 1405-1414
Incorporating evolutionary and threat processes into crop wild relatives conservation

Crop wild relatives’ genetic diversity is usually not considered in conservation planning. Here, the authors introduce an approach to identify conservation areas based on evolutionary and threat processes, by developing proxies of genetic differentiation, and including taxa’s habitat preferences.

Wolke Tobón-Niedfeldt
Alicia Mastretta-Yanes
Patricia Koleff
ResearchOpen Access21 Oct 2022
Nature Communications

Volume: 13, P: 1-18
Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Andrey Ziyatdinov
Jason Torres
Roberto Tapia-Conyer
Amendments and CorrectionsOpen Access08 Feb 2024
Nature

Volume: 626, P: E18
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Alterations in the tumour suppressor genes STK11 and/or KEAP1 can identify patients with advanced non-small-cell lung cancer who are likely to benefit from combinations of PD-(L)1 and CTLA4 immune checkpoint inhibitors added to chemotherapy.

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
ResearchOpen Access09 Oct 2024
Nature

Volume: 635, P: 462-471
Vector surveillance during a major chikungunya outbreak in northwestern São Paulo state, Brazil

Cecília Artico Banho
Maisa Carla Pereira Parra
Maurício Lacerda Nogueira
ResearchOpen Access14 Nov 2025
npj Viruses

Volume: 3, P: 1-12
Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
Amendments and CorrectionsOpen Access27 Feb 2025
Nature

Volume: 639, P: E19
Cross-species and mammal-to-mammal transmission of clade 2.3.4.4b highly pathogenic avian influenza A/H5N1 with PB2 adaptations

Highly pathogenic H5N1 avian influenza lineage 2.3.4.4b has spread through the Americas in birds since 2021 with frequent spillover into mammals. Here, the authors characterise the dissemination of the virus in Chile and find evidence of sustained transmission between mammals.

Catalina Pardo-Roa
Martha I. Nelson
Rafael A. Medina
ResearchOpen Access06 Mar 2025
Nature Communications

Volume: 16, P: 1-15
Climate-driven global redistribution of an ocean giant predicts increased threat from shipping

The authors use long-term satellite tracking to project climate-induced shifts in whale shark distributions and understand their potential future risk of ship-strike. Under high-emission scenarios, the movement of sharks to current range-edge habitat is linked to 15,000-fold increased co-occurrence with ships.

Freya C. Womersley
Lara L. Sousa
David W. Sims
ResearchOpen Access07 Oct 2024
Nature Climate Change

Volume: 14, P: 1282-1291
Treatment intervals with first-generation anti-vascular endothelial growth factor drugs: evaluating the unmet need in a real-world neovascular age-related macular degeneration national database

Javier Zarranz-Ventura
Gonzaga Garay-Aramburu
Ana Campo Gesto
ResearchOpen Access16 Oct 2025
Eye

Volume: 39, P: 3306-3313
Risk of endocarditis among patients with coagulase-negative Staphylococcus bacteremia

Antonio Ramos-Martínez
Patricia González-Merino
Jorge Calderón-Parra
ResearchOpen Access20 Sept 2023
Scientific Reports

Volume: 13, P: 1-7
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020

Analysis of the spread of the 20E (EU1) variant of SARS-CoV-2 through Europe suggests that international travel and insufficient containment, rather than increased transmissibility, led to a resurgence of infections.

Emma B. Hodcroft
Moira Zuber
Richard A. Neher
Research07 Jun 2021
Nature

Volume: 595, P: 707-712
Concordance of the risk of neonatal respiratory morbidity assessed by quantitative ultrasound lung texture analysis in fetuses of twin pregnancies

Ana L. Moreno-Espinosa
Ameth Hawkins-Villarreal
Montse Palacio
ResearchOpen Access30 May 2022
Scientific Reports

Volume: 12, P: 1-9
Large-scale recent expansion of European patrilineages shown by population resequencing

The origins and antiquity of the people of Europe has been much debated. Here, the authors sequence 3.7 Mb of the Y chromosome in over 300 Europeans and Middle Easterners and show a recent, continent-wide and male-specific expansion dating back to the Bronze Age.

Chiara Batini
Pille Hallast
Mark A. Jobling
ResearchOpen Access19 May 2015
Nature Communications

Volume: 6, P: 1-8
Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

Sebastian Moguilner
Sandra Baez
Agustin Ibanez
Amendments and CorrectionsOpen Access16 Sept 2024
Nature Medicine

Volume: 30, P: 3779
Association between uric acid and referable diabetic retinopathy in patients with type 2 diabetes

David Rivera-De-la-Parra
Sergio Hernández-Jiménez
David Kershenobich-Stalnikowitz
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-6
A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection

Most conventional tuberculosis diagnostic tests rely on difficult to obtain sputum samples. In this proof-of-concept study, authors analyse whether pulmonary tuberculosis can be detected using exhaled breath condensate samples.

Sergio Fabián Mosquera-Restrepo
Sophie Zuberogoïtia
Jérôme Nigou
ResearchOpen Access14 Dec 2022
Nature Communications

Volume: 13, P: 1-15
De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera)

Unlike most plants, date palms are either male or female. Assembly of a draft date palm genome, the first for a member of the order Arecales, reveals loci linked to gender and provides markers for improving traits such as fruit quality and ripening time.

Eman K Al-Dous
Binu George
Joel A Malek
ResearchOpen Access29 May 2011
Nature Biotechnology

Volume: 29, P: 521-527
Mitigating noise in digital and digital–analog quantum computation

The authors explore the digital-analog quantum computing paradigm, which combines fast single-qubit gates with the natural dynamics of quantum devices. They find the digital-analog paradigm more robust against certain experimental imperfections than the standard fully-digital one and successfully apply error mitigation techniques to this approach.

Paula García-Molina
Ana Martin
Mikel Sanz
ResearchOpen Access06 Oct 2024
Communications Physics

Volume: 7, P: 1-10
Building a hereditary cancer program in Colombia: analysis of germline pathogenic and likely pathogenic variants spectrum in a high-risk cohort

María Carolina Sanabria-Salas
Ana Lucía Rivera-Herrera
Luis G. Carvajal-Carmona
ResearchOpen Access10 Mar 2025
European Journal of Human Genetics

Volume: 33, P: 913-929
First large-scale study reveals important losses of managed honey bee and stingless bee colonies in Latin America

Fabrice Requier
Malena Sibaja Leyton
Karina Antúnez
ResearchOpen Access02 May 2024
Scientific Reports

Volume: 14, P: 1-15
A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism

Stephan Nopp
Clemens Spielvogel
H. M. Bui
ResearchOpen Access24 Sept 2025
Scientific Reports

Volume: 15, P: 1-12
Genetic diversity and comparative genomics across Leishmania (Viannia) species

Population genomics and chromosome-level genome assemblies for Leishmania strains circulating in Colombia reveal population structure, copy number variation and evolution of amastin families.

Laura Natalia Gonzalez-Garcia
Maria Paula Rodriguez
Jorge Duitama
ResearchOpen Access14 Jun 2025
Communications Biology

Volume: 8, P: 1-14
100 hours of astronomy at the Mexican northern border

I. Villicaña-Pedraza
J. Sáenz
R. Aparicio
Correspondence26 Aug 2019
Nature Astronomy

Volume: 4, P: 4-5
Neolithic pastoralism and plant community interactions at high altitudes of the Pyrenees, southern Europe

Continuous presence of domesticated animals at high altitudes in southern Europe starting 6500 years ago, and dominance of open landscapes since 4200 years before present is shown by sedimentary DNA dated between 12,200 and 1300 years before present.

Irene Julián-Posada
Graciela Gil-Romera
Penélope González-Sampériz
ResearchOpen Access24 Jan 2025
Communications Earth & Environment

Volume: 6, P: 1-10
Adenovirus 36 prevalence and association with human obesity: a systematic review

Jaime da Silva Fernandes
Fabiana Schuelter-Trevisol
Daisson José Trevisol
Research22 Mar 2021
International Journal of Obesity

Volume: 45, P: 1342-1356
Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism

Yenniffer Ávalos
María Paz Hernández-Cáceres
Eugenia Morselli
ResearchOpen Access28 Jul 2022
Cell Death & Disease

Volume: 13, P: 1-13
Enhanced mGluR₅ intracellular activity causes psychiatric alterations in Niemann Pick type C disease

Ana Toledano-Zaragoza
Violeta Enriquez-Zarralanga
María Dolores Ledesma
ResearchOpen Access23 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-13
Epidemiology of GII.4 and GII.2 norovirus outbreaks in closed and semi-closed institutions in 2017 and 2018

Thais Cornejo-Sánchez
Núria Soldevila
Mercé de Simón
ResearchOpen Access30 Jan 2023
Scientific Reports

Volume: 13, P: 1-8
Genetic variants regulating the immune response improve the prediction of COVID-19 severity provided by clinical variables

Pablo Delgado-Wicke
Sara Fernández de Córdoba-Oñate
Isabel Iturrate
ResearchOpen Access05 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study

Luis Felipe Reyes
Alejandro Rodriguez
Neus Guasch
ResearchOpen Access21 Apr 2023
Scientific Reports

Volume: 13, P: 1-15
Descriptive study on oral health and pathologies in vulnerable migrant adolescents from North and West Africa

Elena Sirumal
Susell Parra-Rojas
Rocío Trinidad Velázquez-Cayón
ResearchOpen Access27 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
Detection of SARS-CoV-2 RNA in serum is associated with increased mortality risk in hospitalized COVID-19 patients

Diego A. Rodríguez-Serrano
Emilia Roy-Vallejo
Jesús Delgado Valdueza
ResearchOpen Access23 Jun 2021
Scientific Reports

Volume: 11, P: 1-11
Bone health in patients with kidney stones

The presence of urolithiasis has been shown to be associated with an increased risk of bone fracture in men and women, particularly in adolescent males and females aged 30–39 years and 70–79 years. This increased risk of fracture in patients with urolithiasis may have important implications for public health.

Miguel Angel Arrabal-Polo
Miguel Arrabal-Martin
News & Views09 Dec 2014
Nature Reviews Urology

Volume: 12, P: 9-10
Evidence of natural Zika virus infection in neotropical non-human primates in Brazil

Ana Carolina B. Terzian
Nathalia Zini
Maurício Lacerda Nogueira
ResearchOpen Access30 Oct 2018
Scientific Reports

Volume: 8, P: 1-15
Dynamic clade transitions and the influence of vaccination on the spatiotemporal circulation of SARS-CoV-2 variants

Cecília Artico Banho
Beatriz de Carvalho Marques
Maurício Lacerda Nogueira
ResearchOpen Access10 Aug 2024
npj Vaccines

Volume: 9, P: 1-12
Author Correction: Cryogenic electron microscopy reveals morphologically distinct subtypes of extracellular vesicles among porcine ejaculate fractions

Ana Parra
Isabel Barranco
Jordi Roca
Amendments and CorrectionsOpen Access09 Aug 2024
Scientific Reports

Volume: 14, P: 1
Insights into the mechanisms underlying aberrant SOX11 oncogene expression in mantle cell lymphoma

Roser Vilarrasa-Blasi
Núria Verdaguer-Dot
José Ignacio Martin-Subero
Research28 Aug 2021
Leukemia

Volume: 36, P: 583-587
Preventive bundle approach decreases the incidence of ventilator-associated pneumonia in newborn infants

Alejandro Pinilla-González
Álvaro Solaz-García
María Cernada
Research25 May 2021
Journal of Perinatology

Volume: 41, P: 1467-1473
Cryogenic electron microscopy reveals morphologically distinct subtypes of extracellular vesicles among porcine ejaculate fractions

Ana Parra
Isabel Barranco
Jordi Roca
ResearchOpen Access13 Jul 2024
Scientific Reports

Volume: 14, P: 1-12
Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

Alfredo Guillén-Del-Castillo
Manuel López Meseguer
José Antonio Vargas Hitos
ResearchOpen Access28 Mar 2022
Scientific Reports

Volume: 12, P: 1-11

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