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Showing 1–7 of 7 results
Advanced filters: Author: Ana Senra Clear advanced filters

  • Nicotine reduces food intake and increases energy expenditure in brown adipose tissue. Here the authors show that nicotine also induces white adipose tissue browning via central kappa opioid receptor action.

    • Patricia Seoane-Collazo
    • Laura Liñares-Pose
    • Miguel López
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Extended exposure to breastfeeding in rodent pups protects them from diet-induced obesity in adulthood by increasing thermogenesis and energy expenditure. This is mediated by liver-derived FGF21 signalling to the lateral hypothalamic area.

    • Veronica Pena-Leon
    • Cintia Folgueira
    • Luisa M. Seoane
    ResearchOpen Access
    Nature Metabolism
    Volume: 4, P: 901-917

  • p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase.

    • Maria J. Gonzalez-Rellan
    • Marcos F. Fondevila
    • Ruben Nogueiras
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-21

  • Here, the authors present results of the ZiBRA-2 project (https://www.zibra2project.org) which is an arbovirus surveillance project, across the Midwest of Brazil using a mobile genomics laboratory, combined with a genomic surveillance training program that targeted post-graduate students, laboratory technicians, and health practitioners in universities and laboratories.

    • Talita Émile Ribeiro Adelino
    • Marta Giovanetti
    • Luiz Carlos Junior Alcantara
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Folgueira et al. show that dopamine signalling in the lateral hypothalamic area and the zona incerta reduces body weight and increases energy expenditure by increasing brown adipose tissue thermogenesis in rodents. Weight loss and increased energy expenditure were also observed in patients treated with a dopamine receptor 2 agonist.

    • Cintia Folgueira
    • Daniel Beiroa
    • Ruben Nogueiras
    Research
    Nature Metabolism
    Volume: 1, P: 811-829

  • Emerging studies suggest that p53 is an important regulator of energy metabolism, yet there is little known about the metabolic function of this tumor suppressor in the hypothalamus. Here, authors illustrate that p53, specifically in AgRP neurons, is required for adaptation to diet-induced obesity.

    • Mar Quiñones
    • Omar Al-Massadi
    • Ruben Nogueiras
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16