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Showing 1–6 of 6 results
Advanced filters: Author: Anatol W. Fritsch Clear advanced filters

  • Cervix and breast carcinomas are highly heterogeneous in their mechanical properties across scales. This heterogeneity provides the tumour with stability and room for cell motility.

    • Thomas Fuhs
    • Franziska Wetzel
    • Josef A. Käs
    Research
    Nature Physics
    Volume: 18, P: 1510-1519

  • Uechi et al. found that a small-molecule lipoamide dissolves stress granules (SGs) by targeting SFPQ, a redox-sensitive disordered SG protein, alleviating pathological phenotypes caused by amyotrophic lateral sclerosis-associated FUS and TDP-43 mutants.

    • Hiroyuki Uechi
    • Sindhuja Sridharan
    • Richard J. Wheeler
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 1577-1588

  • HDAC6 modulates acetylation at multiple lysine residues in the N-terminal intrinsically disordered region of RNA helicase DDX3X to regulate liquid–liquid phase separation and stress granule maturation.

    • Makoto Saito
    • Daniel Hess
    • Patrick Matthias
    Research
    Nature Chemical Biology
    Volume: 15, P: 51-61

  • Phase-separated compartments have long been proposed as precursors to cellular life. Now, it has been shown that RNA–peptide protocells are more robust when formed using shorter (rather than longer) peptides, and that peptide sequence determines the functional materials properties of these compartments.

    • Juan M. Iglesias-Artola
    • Björn Drobot
    • Moritz Kreysing
    ResearchOpen Access
    Nature Chemistry
    Volume: 14, P: 407-416

  • During the early development of an organism, some cells are fated to grow while other seemingly healthy cells die. Experiments and theory now reveal that a hydraulic instability is the key to this decision.

    • Nicolas T. Chartier
    • Arghyadip Mukherjee
    • Stephan W. Grill
    ResearchOpen Access
    Nature Physics
    Volume: 17, P: 920-925