Nature Search

Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP)

Gunilla Larsson
L. Anders Svensson
Per Olof Nyman
Research01 Jun 1996
Nature Structural Biology

Volume: 3, P: 532-538
Crystal structure of catechol O-methyltransferase

Jukka Vidgren
L. Anders Svensson
Anders Liljas
Research24 Mar 1994
Nature

Volume: 368, P: 354-358
Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids

Ross L. Coppel
Alan F. Cowman
Robin F. Anders
Research22 Dec 1983
Nature

Volume: 306, P: 751-756
Crystal structure of a ribosomal component at 2.6 Å resolution

Marie Leijonmarck
Stig Eriksson
Anders Liljas
Research01 Aug 1980
Nature

Volume: 286, P: 824-826
Unusual clustering of carboxyl side chains in the core of iron-free ribonucleotide reductase

Anders Åberg
Pär Nordlund
Hans Eklund
Research01 Jan 1993
Nature

Volume: 361, P: 276-278
Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts

Anders Fjose
William J. McGinnis
Walter J. Gehring
Research24 Jan 1985
Nature

Volume: 313, P: 284-289
Immune sera recognize on erythrocytes a Plasmodium falciparum antigen composed of repeated amino acid sequences

Ross L. Coppel
Alan F. Cowman
Graham V. Brown
Research30 Aug 1984
Nature

Volume: 310, P: 789-792
GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility

Autoimmune Addison’s disease is a rare complex disease, which has not yet been characterized by non-biased genetic studies. Here, the authors perform the first GWAS for the disease, identifying nine loci including two coding variants in the gene Autoimmune Regulator (AIRE).

Daniel Eriksson
Ellen Christine Røyrvik
Eystein Sverre Husebye
ResearchOpen Access11 Feb 2021
Nature Communications

Volume: 12, P: 1-14
Discrimination between antibodies to HIV and to related retroviruses using site-directed serology

Erling Norrby
Gunnel Biberfeld
Richard Lerner
Research17 Sept 1987
Nature

Volume: 329, P: 248-250
Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Narcolepsy has genetic and environmental risk factors, but the specific genetic risk loci and interaction with environmental triggers are not well understood. Here, the authors identify genetic loci for narcolepsy, suggesting infection as a trigger and dendritic and helper T cell involvement.

Hanna M. Ollila
Eilon Sharon
Emmanuel J. Mignot
ResearchOpen Access15 May 2023
Nature Communications

Volume: 14, P: 1-13
Synthetic standard aided quantification and structural characterization of amyloid-beta glycopeptides enriched from cerebrospinal fluid of Alzheimer’s disease patients

Jonas Nilsson
Gunnar Brinkmalm
Göran Larson
ResearchOpen Access02 Apr 2019
Scientific Reports

Volume: 9, P: 1-13
Structural basis for inhibition of an archaeal CRISPR–Cas type I-D large subunit by an anti-CRISPR protein

In type I-D CRISPR–Cas systems, the nuclease and helicase activities are carried out by separate subunits. The crystal structure of Sulfolobus islandicus type I-D large subunit Cas10d, containing a nuclease domain, reveals unusual architecture. The structure of Cas10d in complex with anti-CRISPR protein AcrID1 suggests that the latter sequesters Cas10d in a nonfunctional state.

M. Cemre Manav
Lan B. Van
Ditlev E. Brodersen
ResearchOpen Access25 Nov 2020
Nature Communications

Volume: 11, P: 1-10
Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation

A vesicle trafficking Rab11 effector switch is important for ciliogenesis. Here, the authors report a ciliopathy-related disorder caused by variants in WDR44, a Rab11 effector. WDR44 variants show higher affinity for Rab11 and can impair ciliogenesis.

Andrea Accogli
Saurabh Shakya
Christopher J. Westlake
ResearchOpen Access08 Jan 2024
Nature Communications

Volume: 15, P: 1-20
High oscillator strength interlayer excitons in two-dimensional heterostructures for mid-infrared photodetection

Formation of interlayer excitons with high oscillator strength in a WS₂/HfS₂ heterostructure enables the realization of high-responsivity room-temperature mid- and long-wavelength infrared photodetectors.

Steven Lukman
Lu Ding
Jinghua Teng
Research29 Jun 2020
Nature Nanotechnology

Volume: 15, P: 675-682
Lysine methylation of VCP by a member of a novel human protein methyltransferase family

Methyltransferases modify cellular proteins in addition to DNA and histones. These authors identify a new family of lysine-specific methyltransferases and show that a member of this family, which is associated with tumour metastasis, methylates the ATP-dependent protein chaperone VCP/p97.

Stefan Kernstock
Erna Davydova
Pål Ø. Falnes
Research04 Sept 2012
Nature Communications

Volume: 3, P: 1-11
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Multiancestry genome-wide association analyses identify new risk loci for stroke and stroke subtypes. Fine mapping and bioinformatics analyses of these risk loci point to mechanisms not previously implicated in stroke pathophysiology.

Rainer Malik
Ganesh Chauhan
Martin Dichgans
Research12 Mar 2018
Nature Genetics

Volume: 50, P: 524-537
Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunovic
Anna Wredenberg
Nils-Göran Larsson
Research27 May 2004
Nature

Volume: 429, P: 417-423
The International Primary Care Respiratory Group (IPCRG) Research Needs Statement 2010

Hilary Pinnock
Mike Thomas
Sian Williams
Research31 May 2010
Primary Care Respiratory Journal

Volume: 19, P: S1-S20
Protein-altering germline mutations implicate novel genes related to lung cancer development

In lung cancer, relatively few germline mutations are known to impact risk. Here the authors looked at rare variants in 39,146 individuals and find novel germline mutations associated with risk, as well as implicating ATM and a new candidate gene for lung cancer risk.

Xuemei Ji
Semanti Mukherjee
Christopher I. Amos
ResearchOpen Access11 May 2020
Nature Communications

Volume: 11, P: 1-14
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Both rare and common variants contribute to the aetiology of complex traits such as type 2 diabetes (T2D). Here, the authors examine the effect of coding variation on glycaemic traits and T2D, and identify low-frequency variation in GLP1Rsignificantly associated with these traits.

Jennifer Wessel
Audrey Y Chu
Mark O Goodarzi
ResearchOpen Access29 Jan 2015
Nature Communications

Volume: 6, P: 1-16
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

A subunit of the ARC/Mediator co-activator complex is a key effector of the SREBP transcription factor during regulation of lipid homeostasis in human cells and Caenorhabditis elegans. The SREBP activation domain directly targets a KIX domain on ARC105/MED15

Fajun Yang
Bryan W. Vought
Anders M. Näär
Research21 Jun 2006
Nature

Volume: 442, P: 700-704
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Georg B. Ehret
Patricia B. Munroe
Toby Johnson
Research11 Sept 2011
Nature

Volume: 478, P: 103-109
Highly Compressed Two-Dimensional Form of Water at Ambient Conditions

Sarp Kaya
Daniel Schlesinger
Anders Nilsson
ResearchOpen Access15 Jan 2013
Scientific Reports

Volume: 3, P: 1-5
Genome-wide association study identifies five susceptibility loci for glioma

Richard Houlston, Melissa Bondy and colleagues identify variants at five loci associated with glioma susceptibility, providing insights into the etiology of this primary brain tumor. The risk loci include common variants near TERT, CDKN2A-CDKN2B and RTEL1.

Sanjay Shete
Fay J Hosking
Richard S Houlston
Research05 Jul 2009
Nature Genetics

Volume: 41, P: 899-904
Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

The chromosome 15q25.1 locus is a leading susceptibility region for lung cancer. Here, the authors interrogate three GWAS cohorts with 42,901 individuals to investigate potential pathological pathways such as gated channel activity and neuroactive ligand receptor interaction in lung cancer etiology.

Xuemei Ji
Yohan Bossé
Christopher I. Amos
ResearchOpen Access13 Aug 2018
Nature Communications

Volume: 9, P: 1-15
The TβRI promotes migration and metastasis through thrombospondin 1 and ITGAV in prostate cancer cells

Yabing Mu
Anders Wallenius
Maréne Landström
ResearchOpen Access20 Sept 2024
Oncogene

Volume: 43, P: 3321-3334
Biochemical Characterization of Kat1: a Domesticated hAT-Transposase that Induces DNA Hairpin Formation and MAT-Switching

Kishore K. Chiruvella
Naghmeh Rajaei
Stefan U. Åström
ResearchOpen Access23 Feb 2016
Scientific Reports

Volume: 6, P: 1-14
A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

Karen S. Harris
Rosemary F. Guarino
Marilyn A. Anderson
ResearchOpen Access25 Jul 2019
Scientific Reports

Volume: 9, P: 1-13
Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

Rodrigo A. V. Morales
Christopher A. MacRaild
Raymond S. Norton
ResearchOpen Access12 May 2015
Scientific Reports

Volume: 5, P: 1-10
Novel missense ACAN gene variants linked to familial osteochondritis dissecans cluster in the C-terminal globular domain of aggrecan

Eva-Lena Stattin
Karin Lindblom
Anders Aspberg
ResearchOpen Access25 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny

Palaeoproteomic analysis of dental enamel from an Early Pleistocene Stephanorhinus resolves the phylogeny of Eurasian Rhinocerotidae, by enabling the reconstruction of molecular evolution beyond the limits of ancient DNA preservation.

Enrico Cappellini
Frido Welker
Eske Willerslev
Research11 Sept 2019
Nature

Volume: 574, P: 103-107
An ultra low frequency spike timing dependent plasticity based approach for reducing alcohol drinking

Anders J. Asp
Suelen Lucio Boschen
J. Luis Lujan
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-17
B3GALNT2 is a gene associated with congenital muscular dystrophy with brain malformations

Carola Hedberg
Anders Oldfors
Niklas Darin
Research02 Oct 2013
European Journal of Human Genetics

Volume: 22, P: 707-710
Transposon-mediated BAC transgenesis in zebrafish

Maximiliano L Suster
Gembu Abe
Koichi Kawakami
Protocols01 Dec 2011
Nature Protocols

Volume: 6, P: 1998-2021
A quadruple dissociation of reward-related behaviour in mice across excitatory inputs to the nucleus accumbens shell

An optogenetic, spatial self-stimulation task in mice reveals how information carried by distinct inputs to the nucleus accumbens shell is potentially integrated to drive behavioural responses.

Erin B. Lind
Brian M. Sweis
Mark J. Thomas
ResearchOpen Access30 Jan 2023
Communications Biology

Volume: 6, P: 1-12
Mechanism of action for N-substituted benzamide-induced apoptosis

A R Olsson
H Lindgren
T Leanderson
ResearchOpen Access12 Mar 2002
British Journal of Cancer

Volume: 86, P: 971-978
Medium- and high-intensity rTMS reduces psychomotor agitation with distinct neurobiologic mechanisms

Alesha Heath
Daniel R. Lindberg
Paul E. Croarkin
ResearchOpen Access05 Jul 2018
Translational Psychiatry

Volume: 8, P: 1-13
Environmental factors in declining human fertility

This article discusses trends in human reproductive behaviour and health that are associated with infertility. These changes have occurred over a period of only a couple of generations, so environmental factors are suggested to have a role.

Niels E. Skakkebæk
Rune Lindahl-Jacobsen
Anders Juul
Reviews15 Dec 2021
Nature Reviews Endocrinology

Volume: 18, P: 139-157
Circulating vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort

Anouar Fanidi
David C. Muller
Mattias Johansson
ResearchOpen Access04 Nov 2016
Scientific Reports

Volume: 6, P: 1-11
Concurrent anxiety in patients with major depression and cerebral serotonin 4 receptor binding. A NeuroPharm-1 study

Kristin Köhler-Forsberg
Brice Ozenne
Martin B. Jørgensen
ResearchOpen Access11 Jul 2022
Translational Psychiatry

Volume: 12, P: 1-8

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