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Therapeutic potential of human mesenchymal stromal cell-derived mitochondria in a rat model of surgical digestive fistula

Antoine Mariani
Augustin Guichard
Sabah Mozafari
ResearchOpen Access09 Aug 2025
Scientific Reports

Volume: 15, P: 1-15
Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2

The guanine exchange factor DOCK2 regulates the development of immunomodulatory function in human stromal cells (mesenchymal stem/progenitor cells (MSPC) and fibroblasts), as demonstrated in three models.

Cornelia Scharler
Rodolphe Poupardin
Dirk Strunk
ResearchOpen Access15 Nov 2022
Communications Biology

Volume: 5, P: 1-10

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Therapeutic potential of human mesenchymal stromal cell-derived mitochondria in a rat model of surgical digestive fistula

Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2

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