Salmonellae cause systemic diseases by invading and replicating inside epithelial cells and macrophages. Two functionally distinct type III secretion systems that are encoded onSalmonella pathogenicity islands 1 and 2 transfer Salmonellaspp. effector proteins into host cells. The dynamic molecular interplay between these bacterial effectors and host responses is discussed in this Review.
- Andrea Haraga
- Maikke B. Ohlson
- Samuel I. Miller
