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Advanced filters: Author: Andrea Li Greci Clear advanced filters

  • TET mediated RNA-hydroxymethylation (5hmC) has been detected in mammals, but its physiological role remains unclear. Here the authors map 5hmC during embryonic stem cell (ESC) differentiation and find that Tet-mediated RNA hydroxymethylation reduces the stability of crucial pluripotency related transcripts.

    • Jie Lan
    • Nicholas Rajan
    • François Fuks
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15