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Showing 1–6 of 6 results
Advanced filters: Author: Andreas Rechtsteiner Clear advanced filters

  • Antibodies are a primary tool to assess histone post-translational modifications. However, different antibodies and batches might vary in their ability to recognize those modifications, depending on the kind of assay used. Now a systematic analysis of different antibodies and an open database containing the validation results are presented.

    • Thea A Egelhofer
    • Aki Minoda
    • Jason D Lieb
    Research
    Nature Structural & Molecular Biology
    Volume: 18, P: 91-93

  • The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.

    • Kiyomi Raye Kaneshiro
    • Andreas Rechtsteiner
    • Susan Strome
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-9

  • Centromere identity is thought to be epigenetically propagated by stable inheritance of nucleosomes containing the histone variant CENP-A; the authors propose a different model here in which germline transcription defines the genomic regions that exclude CENP-A incorporation during embryogenesis in the holocentric worm Caenorhabditis elegans.

    • Reto Gassmann
    • Andreas Rechtsteiner
    • Arshad Desai
    Research
    Nature
    Volume: 484, P: 534-537

  • Paternal contributions to epigenetic inheritance via nucleosomes are poorly understood, as sperm in many organisms replace the majority of nucleosomes with protamines. Here the authors provide evidence that Caenorhabditis elegans sperm retain histone packaging of the genome and provide a histone-based epigenetic memory that is important for germ cell development in offspring.

    • Tomoko M. Tabuchi
    • Andreas Rechtsteiner
    • Susan Strome
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • A large collection of new modENCODE and ENCODE genome-wide chromatin data sets from cell lines and developmental stages in worm, fly and human are analysed; this reveals many conserved features of chromatin organization among the three organisms, as well as notable differences in the composition and locations of repressive chromatin.

    • Joshua W. K. Ho
    • Youngsook L. Jung
    • Peter J. Park
    ResearchOpen Access
    Nature
    Volume: 512, P: 449-452