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Showing 1–5 of 5 results

Advanced filters: Author: Andreas Reicher Clear advanced filters

Pooled multicolour tagging for visualizing subcellular protein dynamics

Reicher, Reiniš et al. report a method for multicolour tagging using genome-scale intron-targeting sgRNA libraries that, in combination with computer vision, enables the systematic detection of protein localization changes.

Andreas Reicher
Jiří Reiniš
Stefan Kubicek
ResearchOpen Access19 Apr 2024
Nature Cell Biology

Volume: 26, P: 745-756
Monitoring subcellular protein localization at scale in live cells

In this Tools of the Trade article, Reiniš and Reicher (Kubicek Lab) describe the development of a multicolour protein-tagging strategy that allows live-cell monitoring of multiple proteins.

Jiří Reiniš
Andreas Reicher
Research Highlights10 Jun 2024
Nature Reviews Molecular Cell Biology

Volume: 25, P: 673
Pharmacological perturbation of the phase-separating protein SMNDC1

SMNDC1 is a splicing factor that binds arginine methylation with its Tudor domain. Here, the authors study the protein’s phase-separating behavior and develop small-molecule Tudor domain inhibitors that perturb SMNDC1 function.

Lennart Enders
Marton Siklos
Stefan Kubicek
ResearchOpen Access16 Aug 2023
Nature Communications

Volume: 14, P: 1-19
Conflict experience and resolution underlying obedience to authority

Felix J. Götz
Vanessa Mitschke
Andreas B. Eder
ResearchOpen Access10 Jul 2023
Scientific Reports

Volume: 13, P: 1-12
Benefit of second-line systemic chemotherapy for advanced biliary tract cancer: A propensity score analysis

Florian Moik
Jakob M. Riedl
Florian Posch
ResearchOpen Access03 Apr 2019
Scientific Reports

Volume: 9, P: 1-11