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Showing 1–2 of 2 results
Advanced filters: Author: Andreas Reppas Clear advanced filters

  • Savvopoulos, Scheffner et al. develop a simple model that learns each kidney transplant recipient’s usual kidney function from routine tests and defines a personal failure threshold. This individualized threshold predicts future transplant loss more accurately than fixed cut-offs, helping to identify high-risk patients earlier.

    • Symeon V. Savvopoulos
    • Irina Scheffner
    • Haralampos Hatzikirou
    ResearchOpen Access
    Communications Medicine
    P: 1-14

  • Renal fibrosis is a progressive process with complex etiopathology, causing organ failure. Here authors present a mathematical model, based on an in vitro system faithfully contemplating macrophage-fibroblast interaction and the metabolic-immunologic signals that are affecting kidney fibrosis, that is applicable to kidney transplant failure.

    • Elisa Setten
    • Alessandra Castagna
    • Massimo Locati
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-22