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Advanced filters: Author: Andrei Panin Clear advanced filters

Acinar-specific loss of activating transcription factor 3 restricts KRAS^G12D mediated transcriptional changes and PanIN progression

Mickenzie B. Martin
Fatemeh Mousavi
Christopher L. Pin
ResearchOpen Access06 Nov 2025
Cell Death Discovery

Volume: 11, P: 1-15
Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics

Improved imaging methods are crucial to map pancreatic ductal adenocarcinoma (PDAC). Here, the authors analyse PDAC samples using spatial transcriptomics and proteomics, identify claudin-4 as a potential theranostic target, and develop an imaging agent to track claudin-4 in primary and metastatic PDAC tumours.

James Wang
Jai Woong Seo
Katherine W. Ferrara
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-16
Recurring flood distribution patterns related to short-term Holocene climatic variability

Gerardo Benito
Mark G. Macklin
Christoph Zielhofer
ResearchOpen Access09 Nov 2015
Scientific Reports

Volume: 5, P: 1-8
Current European flood-rich period exceptional compared with past 500 years

Analysis of thousands of historical documents recording floods in Europe shows that flooding characteristics in recent decades are unlike those of previous centuries.

Günter Blöschl
Andrea Kiss
Oliver Wetter
Research22 Jul 2020
Nature

Volume: 583, P: 560-566

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