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Showing 1–2 of 2 results
Advanced filters: Author: Andreia Bates Clear advanced filters

  • Trefoil factor 1 (TFF1) is a protein secreted by the gastric mucosa that protects against gastric tumourigenesis. Here, the authors show that TFF1 inhibits the oncogenic inflammatory response and IL-6-mediated STAT3 activation by interfering with the binding of IL6 to its receptor IL6Rα.

    • Mohammed Soutto
    • Zheng Chen
    • Wael El-Rifai
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15

  • Computational protein design methods are used to generate new candidates for a human respiratory syncytial virus (RSV) vaccine; artificial protein scaffolds that mimic the structure of a RSV epitope are shown to induce RSV-specific neutralizing antibodies in macaques.

    • Bruno E. Correia
    • John T. Bates
    • William R. Schief
    Research
    Nature
    Volume: 507, P: 201-206