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Showing 1–8 of 8 results
Advanced filters: Author: Andres M. Kanner Clear advanced filters

  • The future of the Wada test as a predictor of verbal memory function following epilepsy surgery has been debated for some time. Memory mapping based on functional MRI is emerging as a potential alternative. Here, Andres Kanner examines where functional MRI currently stands in this setting.

    • Andres M Kanner
    Reviews
    Nature Clinical Practice Neurology
    Volume: 4, P: 364-365

  • Psychiatric and neurological comorbidities are relatively common in epilepsy, affecting 30–50% of patients. Neurologists should be able to treat psychiatric comorbidities in patients with epilepsy and identify patients at risk of adverse events from psychotropic medications, because psychiatric care is not available to all patients. In this Review, Andres Kanner discusses the complex relationship between epilepsy and psychiatric and neurological comorbidities, and provides considerations for selection of antiepileptic and psychotropic drugs in patients with epilepsy.

    • Andres M. Kanner
    Reviews
    Nature Reviews Neurology
    Volume: 12, P: 106-116

  • Patients with epilepsy have a higher mortality rate than the general population. A recent population-based study has found that external causes of death, such as suicide and accidental deaths of various types, account for 16% of the deaths in these patients, and that psychiatric comorbidity contributes significantly to their occurrence.

    • Andres M. Kanner
    News & Views
    Nature Reviews Neurology
    Volume: 9, P: 606-608

  • Li et al. develop neural fragility, a networked dynamic system biomarker, for localizing seizures in patients with epilepsy and find that it is more robust compared to traditional features that clinicians and researchers look at in a 91-patient study.

    • Adam Li
    • Chester Huynh
    • Sridevi V. Sarma
    Research
    Nature Neuroscience
    Volume: 24, P: 1465-1474

  • Exome sequencing has found an excess of de novo mutations in the ∼4,000 most intolerant genes in patients with two classical epileptic encephalopathies (infantile spasms and Lennox–Gastaut syndrome); among them are multiple de novo mutations in GABRB3 and ALG13.

    • Andrew S. Allen
    • Samuel F. Berkovic
    • Melodie R. Winawer
    Research
    Nature
    Volume: 501, P: 217-221