Analyses of single-cell, multi-omics datasets have potential to provide new insights into biological processes; however, the integration of these complex datasets represents a considerable challenge. This Review describes the principles underlying the integration of multimodal data measured on the same cell (that is, matched data) and on different cells (unmatched data), outlining developments in computational methods and data visualization approaches.
- Zhen Miao
- Benjamin D. Humphreys
- Junhyong Kim
