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Showing 1–18 of 18 results
Advanced filters: Author: Andrew D. Huberman Clear advanced filters

  • Measuring people's finger patterns may reveal some surprising information.

    • Terrance J. Williams
    • Michelle E. Pepitone
    • S. Marc Breedlove
    Research
    Nature
    Volume: 404, P: 455-456

  • Neurons progressively deteriorate with age and lose resilience to injury. It emerges that treatment with three transcription factors can re-endow neurons in the mature eye with youthful characteristics and the capacity to regenerate.

    • Andrew D. Huberman
    News & Views
    Nature
    Volume: 588, P: 34-36

  • Neurobiologist who advocated for gender equality in science.

    • Andrew D. Huberman
    Comments & Opinion
    Nature
    Volume: 553, P: 282

  • The translation of many messenger RNAs that encode important oncogenes and transcription factors depends on the eIF4A RNA helicase to resolve G-quadruplex structures, implying eIF4A inhibition as an effective cancer therapy.

    • Andrew L. Wolfe
    • Kamini Singh
    • Hans-Guido Wendel
    Research
    Nature
    Volume: 513, P: 65-70

  • A molecular cascade involving the transcription factor SIX6 and its target gene p16INK4a causes the death of neurons that link the eye to the brain. This discovery deepens our understanding of a common form of blindness, glaucoma.

    • Andrew D. Huberman
    • Rana N. El-Danaf
    News & Views
    Nature
    Volume: 527, P: 456-457

  • A study uses light-gated ion channels to control the activity of neurons in each eye, thereby revealing how the timing of neuronal firing dictates whether visual circuits segregate from one another or stay mixed.

    • Rana N El Danaf
    • Andrew D Huberman
    News & Views
    Nature Neuroscience
    Volume: 15, P: 172-174

  • Connections between a specific thalamic structure and the neocortex convey mismatches between internal perceptions and external events. These findings help to define the circuits controlling contextual modulation of visual-motor processing.

    • Nao Ishiko
    • Andrew D Huberman
    News & Views
    Nature Neuroscience
    Volume: 19, P: 177-179

  • GFP reporter lines are useful for labeling specific cell types. Here, the authors developed a method to convert GFP expression directly into Cre recombinase activity. GFP-dependent Cre was delivered via electroporation or AAV to neural tissues in the mouse, and could be used for optogenetic control of specific cell types.

    • Jonathan C Y Tang
    • Stephanie Rudolph
    • Constance L Cepko
    Research
    Nature Neuroscience
    Volume: 18, P: 1334-1341

  • Hans-Guido Wendel and colleagues identify five miRNAs that are capable of promoting T-ALL in a mouse model and that account for the majority of miRNA expression in human T-ALL. They show that these miRNAs produce overlapping and cooperative effects on tumor suppressor genes implicated in the pathogenesis of T-ALL.

    • Konstantinos J Mavrakis
    • Joni Van Der Meulen
    • Hans-Guido Wendel
    Research
    Nature Genetics
    Volume: 43, P: 673-678