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Showing 1–9 of 9 results
Advanced filters: Author: Andrew H. Moberly Clear advanced filters
  • Using dual-color mesoscopic imaging in the neocortex of awake mice, the authors show that cholinergic release and neuronal activity exhibit distinct spatiotemporal patterns that are differentially linked to spontaneous fluctuations in behavioral state.

    • Sweyta Lohani
    • Andrew H. Moberly
    • Jessica A. Cardin
    Research
    Nature Neuroscience
    Volume: 25, P: 1706-1713
  • The Cousa objective is an ultra-long working distance air objective optimized for two- and three-photon imaging. Bypassing challenges caused by water immersion and short working distances, the Cousa enables and improves imaging of diverse specimens.

    • Che-Hang Yu
    • Yiyi Yu
    • Spencer LaVere Smith
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 132-141
  • Integral equations are used in science and engineering to model complex systems with non-local dependencies; however, existing traditional and machine-learning-based methods cannot yield accurate or efficient solutions in several complex cases. Zappala and colleagues introduce a neural-network-based method that can learn an integral operator and its dynamics from data, demonstrating higher accuracy or scalability compared with several state-of-the-art methods.

    • Emanuele Zappala
    • Antonio Henrique de Oliveira Fonseca
    • David van Dijk
    ResearchOpen Access
    Nature Machine Intelligence
    Volume: 6, P: 1046-1062
  • Despite their discovery in the 19th century, the islands of Calleja, clusters of densely packed granule cells in the ventral striatum, remain enigmatic. This study reveals that islands of Calleja neurons are critical for grooming control in mice.

    • Yun-Feng Zhang
    • Luigim Vargas Cifuentes
    • Minghong Ma
    Research
    Nature Neuroscience
    Volume: 24, P: 1699-1710
  • Nasal airflow and olfactory bulb activity are linked to oscillations in cortical areas. This study shows olfactory input and respiration are correlated with oscillation in the prefrontal cortex during freezing behavior in mice, and attenuation of olfactory inputs can increase behavioral freezing.

    • Andrew H. Moberly
    • Mary Schreck
    • Minghong Ma
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10
  • In this study, Mainland and colleagues de-orphan 18 human odorant receptors and find that 68% of these receptors exhibit polymorphisms that affect their function in vitro. They also show that the polymorphisms in one these odorant receptors, OR10G4, affect odor intensity and valence perception thus linking the molecular functioning of a single odorant receptor to human olfactory perception.

    • Joel D Mainland
    • Andreas Keller
    • Hiroaki Matsunami
    Research
    Nature Neuroscience
    Volume: 17, P: 114-120