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Showing 1–12 of 12 results
Advanced filters: Author: Andrew J. Bissette Clear advanced filters

  • Autocatalysis is a process whereby a product accelerates its own formation. Here, the authors describe a system whereby two simple components combine irreversibly to give a more complex, amphiphilic product, leading to autocatalytically active micelles.

    • Andrew J. Bissette
    • Barbara Odell
    • Stephen P. Fletcher
    Research
    Nature Communications
    Volume: 5, P: 1-8

    • Andrew Bissette
    Research Highlights
    Nature Chemical Biology
    Volume: 17, P: 1212

    • Andrew J. Bissette
    News & Views
    Nature Chemistry
    Volume: 13, P: 728

  • Creating chemical systems that can model living systems is far from easy. However, the evolution of oil droplets in water through the application of artificial selective pressure to produce droplets with dramatically different — yet specific — behaviours, is an encouraging step in this direction.

    • Andrew J. Bissette
    • Stephen P. Fletcher
    News & Views
    Nature Chemistry
    Volume: 7, P: 15-17

  • Small changes in protein structure can have pronounced effects on protein–protein interactions, but quantifying this has only recently become possible. Now, the binding landscapes of three homologous enzyme–inhibitor complexes are quantified and shown to depend on whether the inhibitor binds its natural target or a structurally similar protein.

    • Andrew J. Bissette
    Research HighlightsOpen Access
    Communications Chemistry
    Volume: 4, P: 1-2

  • Molecular replication could offer insight into the fundamentals of evolution, but achieving controlled mutation is difficult. Now, a synthetic replicator that allows for simple control over its mutation rate has been reported.

    • Andrew J. Bissette
    Research HighlightsOpen Access
    Communications Chemistry
    Volume: 4, P: 1-2

  • DNA-templated synthesis of chiral inorganic assemblies often requires chemical modification of the template. Now, a route exploiting the native chemistry of unmodified DNA origami templates provides access to 3D chiral assemblies.

    • Andrew J. Bissette
    Research HighlightsOpen Access
    Communications Chemistry
    Volume: 4, P: 1-2

  • Lewis acid additives such as aluminium can enable fascinating new reactivity in transition metal catalysts, but few catalytic intermediates have been characterised. Now, a nickel-aluminium pincer complex offers new mechanistic insight into transmetalation, and new potential for reactivity.

    • Andrew J. Bissette
    Research HighlightsOpen Access
    Communications Chemistry
    Volume: 4, P: 1-2

  • Controlling molecular conformation through macroscopic mechanical stimulus may have applications in chiroptical devices, but achieving this in a 3D material is challenging. Now, a quantitative relationship between stretching of an elastomer and reversible conformational changes of a crosslinked molecule has been established.

    • Andrew J. Bissette
    Research HighlightsOpen Access
    Communications Chemistry
    Volume: 3, P: 1-2

  • Mass spectrometry allows the pattern of glycosylation in proteins to be mapped, but can be limited by the lability of glycosidic bonds. Now, a method exploiting this lability allows for direct mapping of glycan moieties in glycoproteins.

    • Andrew J. Bissette
    Research HighlightsOpen Access
    Communications Chemistry
    Volume: 3, P: 1-2