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Showing 1–3 of 3 results
Advanced filters: Author: Andrew M. Masteller Clear advanced filters

  • It is shown that mice deficient for β8 integrin develop colitis, and that β8 needs to be expressed by dendritic cells rather than T cells for colitis to develop. In addition, a decrease of T cells in the gut but not adjacent lymph nodes in diseased animals is shown. It is concluded that αVβ8-mediated integrin activation of dendritic cells is essential for prevention of colitis-inducing immune dysfunction.

    • Mark A. Travis
    • Boris Reizis
    • Dean Sheppard
    Research
    Nature
    Volume: 449, P: 361-365

  • The role of developmental pathways in medulloblastoma tumours (MB) with sonic hedgehog (SHH) activation remains to be explored. Here, the authors perform multi-omic analysis and characterise the key transcriptomic and metabolic patterns of highly differentiated cells in SHH MBs.

    • Maxwell P. Gold
    • Winnie Ong
    • Ernest Fraenkel
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20

  • Earth’s largest dune fields are set to become less dynamic on average over this century due to anthropogenic climate change, with no future action able to mitigate this effect, as predicted by the newest iteration of CMIP models.

    • Andrew Gunn
    • Amy East
    • Douglas J. Jerolmack
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-7