Strained cyclic allenes are short-lived intermediates that confine a functional group with a preferred linear geometry, an allene, into a small ring, inducing strain-driven reactivity. Now, 2,3-azacyclic and 2,3-oxacyclic allenes are generated and trapped using cycloaddition reactions, generating complex heterocycles that bear a large fraction of sp3-hybridized atoms.
- Andrew V. Kelleghan
- Arismel Tena Meza
- Neil K. Garg
