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Showing 1–7 of 7 results
Advanced filters: Author: Andrew Wiersma Clear advanced filters

  • Infection may induce multi-organ thrombosis, but the underlying inflammatory mechanism remains elusive. Here, using Salmonella Typhimurium infectious mouse model, the authors reveal organ specific and broad inflammatory events like TNF for thrombosis in liver and spleen.

    • Marisol Perez-Toledo
    • Nonantzin Beristain-Covarrubias
    • Adam F. Cunningham
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Sexual dimorphism in genetic vulnerability to schizophrenia, systemic lupus erythematosus and Sjögren’s syndrome is linked to differential protein abundance from alleles of complement component 4.

    • Nolan Kamitaki
    • Aswin Sekar
    • Steven A. McCarroll
    Research
    Nature
    Volume: 582, P: 577-581

  • In contrast to common bean, tepary bean is highly adapted to heat and drought. Here, the authors assemble the genomes of tepary bean landrace and wild accession, discuss the possible mechanism for resilience to heat stress, and reveal a reduced disease resistance gene repertoire.

    • Samira Mafi Moghaddam
    • Atena Oladzad
    • Phillip E. McClean
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • The Schizophrenia Psychiatric Genome-Wide Association Study Consortium reports five genetic loci newly associated with risk of schizophrenia, involving 17,836 cases of schizophrenia and 33,859 healthy controls. The new locus with the strongest support of association was located within an intron for microRNA 137, a known regulator of neuronal development. Four other genome-wide significant loci for schizophrenia contain predicted targets of MIR137, suggesting that disruption to pathways involving MIR137 may be an etiologic mechanism in schizophrenia.

    • Stephan Ripke
    • Alan R Sanders
    • Pablo V Gejman
    Research
    Nature Genetics
    Volume: 43, P: 969-976