Nature Search

A new tool called DISSECT for analysing large genomic data sets using a Big Data approach

Availability of computing power can limit computational analysis of large genetic and genomic datasets. Here, Canela-Xandri, et al. describe a software called DISSECT that is capable of analyzing large-scale genetic data by distributing the work across thousands of networked computers.

Oriol Canela-Xandri
Andy Law
Albert Tenesa
ResearchOpen Access11 Dec 2015
Nature Communications

Volume: 6, P: 1-6
GM crops: science, politics and communication

Charles J. Arntzen
Andy Coghlan
Michael Rodemeyer
Reviews01 Oct 2003
Nature Reviews Genetics

Volume: 4, P: 839-843
78,000-year-old record of Middle and Later Stone Age innovation in an East African tropical forest

Most of the archaeological record of the Middle to Later Stone Age transition comes from southern Africa. Here, Shipton et al. describe the new site Panga ya Saidi on the coast of Kenya that covers the last 78,000 years and shows gradual cultural and technological change in the Late Pleistocene.

Ceri Shipton
Patrick Roberts
Nicole Boivin
ResearchOpen Access09 May 2018
Nature Communications

Volume: 9, P: 1-8
Purinergic signaling mediates neuroglial interactions to modulate sighs

Sighs are augmented breaths necessary to maintain normal breathing. Here, the authors show that sighs are generated within the preBötzinger complex by emergent network properties that involve neuroglial interactions mediated by purinergic signaling as well as intrinsic and extrinsic modulatory inputs.

Liza J. Severs
Nicholas E. Bush
Jan-Marino Ramirez
ResearchOpen Access31 Aug 2023
Nature Communications

Volume: 14, P: 1-14
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Genome sequence, comparative analysis and haplotype structure of the domestic dog

Kerstin Lindblad-Toh
Claire M Wade
Eric S. Lander
Research08 Dec 2005
Nature

Volume: 438, P: 803-819
Viability and desirability of financing conservation in Africa through fire management

Adopting early dry season fires has been proposed as a means of generating sufficient carbon revenues to pay for conservation in Africa. However, the climatic impact thereof is deeply questionable and may have unforeseen detrimental effects.

Tony Knowles
Nicola Stevens
Sally Archibald
Reviews06 Jan 2025
Nature Sustainability

Volume: 8, P: 226-233
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Multi-dimensional data transmission using inverse-designed silicon photonics and microcombs

The authors demonstrate a multi-dimensional communication scheme that combines wavelength- and mode- multiplexing on photonic integrated circuits using foundry-compatible photonic inverse design and spectrally flattened microcombs

Ki Youl Yang
Chinmay Shirpurkar
Jelena Vučković
ResearchOpen Access21 Dec 2022
Nature Communications

Volume: 13, P: 1-9
Elimination of human rabies in Goa, India through an integrated One Health approach

Dog vaccination is an effective rabies prevention measure, but widespread vaccination campaigns are challenging in settings like India with large free-roaming dog populations. Here, the authors describe a One Health campaign in Goa state which led to a large reduction of cases in dogs and elimination in humans.

A. D. Gibson
G. Yale
R. J. Mellanby
ResearchOpen Access19 May 2022
Nature Communications

Volume: 13, P: 1-13
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease

Cortical thickness is asymmetric, and cortical thinning occurs with age and in disease. Here the authors investigate if both cortices thin at the same rate or if the thicker hemisphere declines faster in aging and in Alzheimer’s disease.

James M. Roe
Didac Vidal-Piñeiro
Michael Vacher
ResearchOpen Access01 Feb 2021
Nature Communications

Volume: 12, P: 1-11
Genomic reconstruction of the SARS-CoV-2 epidemic in England

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
ResearchOpen Access14 Oct 2021
Nature

Volume: 600, P: 506-511
Multilocus heterozygosity and size: a test of hypotheses using triploid Mytilus edulis

Andy R Beaumont
Jennifer E Fairbrother
Kathrin Hoare
Research01 Sept 1995
Heredity

Volume: 75, P: 256-266
Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

Despite the identification of genetic risk loci for late-onset Alzheimer’s disease (LOAD), the genetic architecture and prediction remains unclear. Here, the authors use genetic risk scores for prediction of LOAD across three datasets and show evidence suggesting oligogenic variant architecture for this disease.

Qian Zhang
Julia Sidorenko
Peter M. Visscher
ResearchOpen Access23 Sept 2020
Nature Communications

Volume: 11, P: 1-11
An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells

Calcium phosphate nanoparticles formed naturally in the intestine aid the transport of soluble molecules from the gut lumen to immune cells of the intestinal tissue, and contribute to the immune surveillance and homeostasis of the gut.

Jonathan J. Powell
Emma Thomas-McKay
Laetitia C. Pele
Research09 Mar 2015
Nature Nanotechnology

Volume: 10, P: 361-369
A global assemblage of regional prescribed burn records — GlobalRx

Alice Hsu
Matthew W. Jones
Emma Zerr
ResearchOpen Access01 Jul 2025
Scientific Data

Volume: 12, P: 1-30
Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease

James M. Roe
Didac Vidal-Piñeiro
Michael Vacher
Amendments and CorrectionsOpen Access07 Feb 2022
Nature Communications

Volume: 13, P: 1
“Tossing a coin:” defining the excessive use of short-acting beta₂-agonists in asthma—the views of general practitioners and asthma experts in primary and secondary care

Shauna McKibben
Andy Bush
Chris Griffiths
ResearchOpen Access18 Jul 2018
npj Primary Care Respiratory Medicine

Volume: 28, P: 1-3
Diagnostic accuracy of the Enferplex Bovine Tuberculosis antibody test in cattle sera

Amanda O’Brien
John Clarke
Gordon D. Harkiss
ResearchOpen Access01 Feb 2023
Scientific Reports

Volume: 13, P: 1-13
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Author Correction: “Tossing a coin:” defining the excessive use of short-acting beta2-agonists in asthma—the views of general practitioners and asthma experts in primary and secondary care

Shauna McKibben
Andy Bush
Chris Griffiths
Amendments and CorrectionsOpen Access14 Jan 2019
npj Primary Care Respiratory Medicine

Volume: 29, P: 1
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
Amendments and CorrectionsOpen Access01 Mar 2022
Nature Communications

Volume: 13, P: 1
Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19

Nicholas Parkinson
Natasha Rodgers
Sara Clohisey
ResearchOpen Access18 Dec 2020
Scientific Reports

Volume: 10, P: 1-12
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

James H. R. Farmery
Mike L. Smith
Andy G. Lynch
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-17
A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

Steve Pedrini
Veer B. Gupta
Philip Thomas
ResearchOpen Access25 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
The use of electronic alerts in primary care computer systems to identify the over-prescription of short-acting beta₂-agonists in people with asthma: a protocol for a systematic review

Shauna McKibben
Andy Bush
Chris Griffiths
ProtocolsOpen Access26 Apr 2017
npj Primary Care Respiratory Medicine

Volume: 27, P: 1-3
The use of electronic alerts in primary care computer systems to identify the excessive prescription of short-acting beta₂-agonists for people with asthma: a systematic review

Shauna McKibben
Anna De Simoni
Chris Griffiths
ReviewsOpen Access16 Apr 2018
npj Primary Care Respiratory Medicine

Volume: 28, P: 1-9
Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

James H. R. Farmery
Mike L. Smith
Andy G. Lynch
Amendments and CorrectionsOpen Access03 Sept 2018
Scientific Reports

Volume: 8, P: 1-4

Search

A new tool called DISSECT for analysing large genomic data sets using a Big Data approach

GM crops: science, politics and communication

78,000-year-old record of Middle and Later Stone Age innovation in an East African tropical forest

Purinergic signaling mediates neuroglial interactions to modulate sighs

A second update on mapping the human genetic architecture of COVID-19

Genome sequence, comparative analysis and haplotype structure of the domestic dog

Viability and desirability of financing conservation in Africa through fire management

SARS-CoV-2 evolution during treatment of chronic infection

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Multi-dimensional data transmission using inverse-designed silicon photonics and microcombs

Elimination of human rabies in Goa, India through an integrated One Health approach

Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease

Genomic reconstruction of the SARS-CoV-2 epidemic in England

Multilocus heterozygosity and size: a test of hypotheses using triploid Mytilus edulis

Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells

A global assemblage of regional prescribed burn records — GlobalRx

Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease

“Tossing a coin:” defining the excessive use of short-acting beta₂-agonists in asthma—the views of general practitioners and asthma experts in primary and secondary care

Diagnostic accuracy of the Enferplex Bovine Tuberculosis antibody test in cattle sera

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Author Correction: “Tossing a coin:” defining the excessive use of short-acting beta2-agonists in asthma—the views of general practitioners and asthma experts in primary and secondary care

Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19

Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

The use of electronic alerts in primary care computer systems to identify the over-prescription of short-acting beta₂-agonists in people with asthma: a protocol for a systematic review

The use of electronic alerts in primary care computer systems to identify the excessive prescription of short-acting beta₂-agonists for people with asthma: a systematic review

Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

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