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Showing 1–3 of 3 results
Advanced filters: Author: Angela B. Schmider Clear advanced filters

  • Irisin is shown to mediate beneficial effects on cognitive function associated with exercise and to improve cognitive function in mouse models of Alzheimer’s disease, probably through its direct action in the brain.

    • Mohammad R. Islam
    • Sophia Valaris
    • Christiane D. Wrann
    Research
    Nature Metabolism
    Volume: 3, P: 1058-1070

  • The COPI complex, which has a role in retrograde transport through the Golgi, is shown to also mediate anterograde tubular transport through the Golgi; in response to external stimuli, the small GTPase CDC42 acts as an essential modulator of bidirectional Golgi transport, and promotes the sorting of cargoes destined for anterograde transport into the tubules at the expense of those targeted for retrograde transport.

    • Seung-Yeol Park
    • Jia-Shu Yang
    • Victor W. Hsu
    Research
    Nature
    Volume: 521, P: 529-532