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Showing 1–4 of 4 results

Advanced filters: Author: Angelica Minier-Toribio Clear advanced filters

Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens in male rats

A hallmark of addiction is a propensity for relapse following abstinence. Here, the authors linked specific transcriptional signatures of the nucleus accumbens to different rodent abstinence modalities relevant to cocaine use disorders in humans.

Freddyson J. Martínez-Rivera
Leanne M. Holt
Eric J. Nestler
ResearchOpen Access25 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system

A lipid-nanoparticle-based formulation incorporating engineered lipids containing a blood–brain-barrier-crossing moiety effectively delivers mRNA to neurons and astrocytes following systemic administration in mice.

Chang Wang
Yonger Xue
Yizhou Dong
Research17 Feb 2025
Nature Materials

Volume: 24, P: 1653-1663
Dopamine D1–D2 signalling in hippocampus arbitrates approach and avoidance

Approach versus avoidance responses are driven by D1 and D2 neurons in the ventral hippocampus.

Arthur Godino
Marine Salery
Eric J. Nestler
Research07 May 2025
Nature

Volume: 643, P: 448-457
Effect of the dopamine stabilizer (-)-OSU6162 on potentiated incubation of opioid craving after electric barrier-induced voluntary abstinence

Ida Fredriksson
Sarah V. Applebey
Yavin Shaham
Research06 Jan 2020
Neuropsychopharmacology

Volume: 45, P: 770-779