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Showing 1–19 of 19 results
Advanced filters: Author: Angeliki Chalkiadaki Clear advanced filters

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 411

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 602

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 502

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 222

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 601

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 223

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 410

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 678

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 320

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 321

    • Angeliki Chalkiadaki
    Research Highlights
    Nature Chemical Biology
    Volume: 8, P: 321

  • Sirtuins have emerged as important regulators of various metabolic pathways, linking nutrient signals with cellular responses to energy demands and driving metabolic cycles in reaction to fasting or calorie restriction. This Review describes the latest advances in the understanding of the function of sirtuins in regulating mammalian metabolism with a focus on their role as mediators of nutrient availability.

    • Angeliki Chalkiadaki
    • Leonard Guarente
    Reviews
    Nature Reviews Endocrinology
    Volume: 8, P: 287-296

  • A system employing liquid-handling robotics and an integrated mobile microscope enables the automated culture, sample collection and in situ microscopy imaging of up to ten fluidically coupled organ chips within a standard tissue-culture incubator.

    • Richard Novak
    • Miles Ingram
    • Donald E. Ingber
    Research
    Nature Biomedical Engineering
    Volume: 4, P: 407-420

  • This Review discusses the roles of members of the sirtuin (SIRT) family in cancer biology, which have dichotomous, context-dependent functions as tumour suppressors and oncogenes. Furthermore, the authors discuss the possibility of targeting the sirtuins for anticancer therapy.

    • Angeliki Chalkiadaki
    • Leonard Guarente
    Reviews
    Nature Reviews Cancer
    Volume: 15, P: 608-624