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Showing 1–5 of 5 results
Advanced filters: Author: Angie L Bookout Clear advanced filters

  • Small genes have been ignored for years in the genome of every organism due to experimental and computational limitations. Here, the authors describe a computational tool named Rp3 that integrates two high throughput approaches to identify microproteins encoded by these short genes.

    • Eduardo Vieira de Souza
    • Angie L. Bookout
    • Alan Saghatelian
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Fibroblast growth factor 21 (FGF21) is a cytokine synthesized and released by the liver, muscle and fat and acts both locally and systemically to regulate whole-body metabolism. David Mangelsdorf and his colleagues now show in two separate studies that FGF21 also acts on the region of the brain that regulates circadian rhythm, the suprachiasmatic nucleus, to further regulate whole-body metabolism as well as reproductive function.

    • Bryn M Owen
    • Angie L Bookout
    • David J Mangelsdorf
    Research
    Nature Medicine
    Volume: 19, P: 1153-1156

  • Fibroblast growth factor 21 (FGF21) is a cytokine synthesized and released by the liver, muscle and fat and acts both locally and systemically to regulate whole-body metabolism. David Mangelsdorf and his colleagues now show in two separate studies that FGF21 also acts on the region of the brain that regulates circadian rhythm, the suprachiasmatic nucleus, to further regulate whole-body metabolism as well as reproductive function.

    • Angie L Bookout
    • Marleen H M de Groot
    • Steven A Kliewer
    Research
    Nature Medicine
    Volume: 19, P: 1147-1152