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Showing 1–6 of 6 results
Advanced filters: Author: Anil M. Tuladhar Clear advanced filters

  • A cross-ancestry meta-analysis of genome-wide association studies identifies association signals for stroke and its subtypes at 89 (61 new) independent loci, reveals putative causal genes, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as potential drug targets, and provides cross-ancestry integrative risk prediction.

    • Aniket Mishra
    • Rainer Malik
    • Stephanie Debette
    ResearchOpen Access
    Nature
    Volume: 611, P: 115-123

  • Poststroke dementia is a clinically heterogeneous syndrome with various underlying mechanisms. A better understanding of the pathophysiology of poststroke dementia together with an improved ability to differentiate between various dementia syndromes will be useful for optimizing therapeutic interventions, and for informing patients and carers about treatment options and prognosis.

    • Anil M. Tuladhar
    • Frank-Erik de Leeuw
    News & Views
    Nature Reviews Neurology
    Volume: 6, P: 63-64

  • Cerebral small vessel disease (SVD) is associated with highly heterogeneous clinical symptoms. This Review considers how new advances in structural and functional neuroimaging have revealed ways in which focal lesions can affect remote brain regions and lead to global dysfunction, resulting in the variable presentation of SVD.

    • Annemieke ter Telgte
    • Esther M. C. van Leijsen
    • Frank-Erik de Leeuw
    Reviews
    Nature Reviews Neurology
    Volume: 14, P: 387-398