Nature Search

Molecular insights on the proangiogenic effects of VEGF like growth factor derived from horseshoe crab perivitelline fluid

K. G. Aghila Rani
Hrishikesh Pandit
Taruna Madan
ResearchOpen Access16 Jan 2026
Scientific Reports

Volume: 16, P: 1-13
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein

JNJ-9676—a small-molecule inhibitor targeting coronavirus M protein that shows excellent efficacy in Syrian golden hamster models—binds to and stabilizes the M protein dimer in an altered conformational state between its long and short forms, preventing the release of infectious virus.

Ellen Van Damme
Pravien Abeywickrema
Marnix Van Loock
ResearchOpen Access26 Mar 2025
Nature

Volume: 640, P: 506-513
A supermassive black hole in an ultra-compact dwarf galaxy

Dynamical modelling of the ultra-compact dwarf galaxy M60-UCD1 reveals the presence of a supermassive black hole; this suggests the object is a stripped galaxy nucleus and implies the existence of supermassive black holes in many other ultra-compact dwarf galaxies.

Anil C. Seth
Remco van den Bosch
Jonelle L. Walsh
Research17 Sept 2014
Nature

Volume: 513, P: 398-400
Theories of consciousness

Various theories have been developed for the biological and physical basis of consciousness. In this Review, Anil Seth and Tim Bayne discuss four prominent theoretical approaches to consciousness, namely higher-order theories, global workspace theories, re-entry and predictive processing theories and integrated information theory.

Anil K. Seth
Tim Bayne
Reviews03 May 2022
Nature Reviews Neuroscience

Volume: 23, P: 439-452
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Two stellar-mass black holes in the globular cluster M22

Two flat-spectrum radio sources in the Milky Way globular cluster M22 are thought to be accreting stellar-mass black holes; the identification of two black holes in one cluster shows that the ejection of black holes from clusters is not as efficient as predicted by most models.

Jay Strader
Laura Chomiuk
Anil C. Seth
Research03 Oct 2012
Nature

Volume: 490, P: 71-73
The chromatin landscape of healthy and injured cell types in the human kidney

Comprehensive integration of gene expression with epigenetic features is needed to understand the transition of kidney cells from health to injury. Here, the authors integrate dual single nucleus RNA expression and chromatin accessibility, DNA methylation, and histone modifications to decipher the chromatin landscape of the kidney in reference and adaptive injury cell states, identifying a transcription factor network of ELF3, KLF6, and KLF10 which regulates adaptive repair and maladaptive failed repair.

Debora L. Gisch
Michelle Brennan
Michael T. Eadon
ResearchOpen Access10 Jan 2024
Nature Communications

Volume: 15, P: 1-21
Comprehensive molecular characterization of urothelial bladder carcinoma

This paper reports integrative molecular analyses of urothelial bladder carcinoma at the DNA, RNA, and protein levels performed as part of The Cancer Genome Atlas project; recurrent mutations were found in 32 genes, including those involved in cell-cycle regulation, chromatin regulation and kinase signalling pathways; chromatin regulatory genes were more frequently mutated in urothelial carcinoma than in any other common cancer studied so far.

John N. Weinstein
Rehan Akbani
Greg Eley
ResearchOpen Access29 Jan 2014
Nature

Volume: 507, P: 315-322
Fast-moving stars around an intermediate-mass black hole in ω Centauri

Observations of seven fast-moving stars in the central 3 arcsec (0.08 pc) of ω Centauri indicate an intermediate-mass black hole in ω Centauri.

Maximilian Häberle
Nadine Neumayer
Glenn van de Ven
ResearchOpen Access10 Jul 2024
Nature

Volume: 631, P: 285-288
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank

An integrated data and sample repository for clinical, cellular and multi-omics research from diverse spaceflight missions known as Space Omics and Medical Atlas (SOMA) is presented.

Eliah G. Overbey
JangKeun Kim
Christopher E. Mason
ResearchOpen Access11 Jun 2024
Nature

Volume: 632, P: 1145-1154
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

A pan-cancer genomic analysis reports the effects of structural variations on chromatin domains (TADs). Most TAD disruptions do not result in appreciable changes in expression of nearby genes.

Kadir C. Akdemir
Victoria T. Le
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Genetics

Volume: 52, P: 294-305
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy

The SMC5/6 complex is critical for genome stability. Here, the authors identify mutations in SLF2 and SMC5 as cause of Atelís Syndrome characterized by microcephaly, short stature, anemia, segmented chromosomes and mosaic variegated hyperploidy.

Laura J. Grange
John J. Reynolds
Grant S. Stewart
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-22
Uncovering supramolecular chirality codes for the design of tunable biomaterials

Assembly of amyloids is important in neurodegenerative diseases, but there is limited understanding of how supramolecular chirality is controlled. Here, the authors report the design of peptide derivatives that allow chirality inversion at biologically relevant temperatures.

Stephen J. Klawa
Michelle Lee
Ronit Freeman
ResearchOpen Access26 Jan 2024
Nature Communications

Volume: 15, P: 1-16
Mapping routine measles vaccination in low- and middle-income countries

Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.

Alyssa N. Sbarra
Sam Rolfe
Jonathan F. Mosser
ResearchOpen Access16 Dec 2020
Nature

Volume: 589, P: 415-419
Author Correction: Fast-moving stars around an intermediate-mass black hole in ω Centauri

Maximilian Häberle
Nadine Neumayer
Glenn van de Ven
Amendments and CorrectionsOpen Access17 Sept 2024
Nature

Volume: 634, P: E1
Expanded encyclopaedias of DNA elements in the human and mouse genomes

The authors summarize the data produced by phase III of the Encyclopedia of DNA Elements (ENCODE) project, a resource for better understanding of the human and mouse genomes.

Federico Abascal
Reyes Acosta
Zhiping Weng
ResearchOpen Access29 Jul 2020
Nature

Volume: 583, P: 699-710
Activity in perceptual classification networks as a basis for human subjective time perception

How the brain tracks the passage of time remains unclear. Here, the authors show that tracking activation changes in a neural network trained to recognize objects (similar to the human visual system) produces estimates of duration that are subject to human-like biases.

Warrick Roseboom
Zafeirios Fountas
Anil K. Seth
ResearchOpen Access17 Jan 2019
Nature Communications

Volume: 10, P: 1-9
A science of consciousness beyond pseudo-science and pseudo-consciousness

The scientific study of consciousness was sanctioned as an orthodox field of study only three decades ago. Since then, a variety of prominent theories have flourished, including integrated information theory, which has been recently accused of being pseudoscience by more than 100 academics. Here we critically assess this charge and offer thoughts to elevate the clash into positive lessons for our field.

Alex Gomez-Marin
Anil K. Seth
Comments & Opinion10 Mar 2025
Nature Neuroscience

Volume: 28, P: 703-706
Catalytic diversity in self-propagating peptide assemblies

Simple peptides are shown to assemble into well-defined amyloid phases with paracrystalline surfaces that can catalyse reactions in an enantioselective manner. Modifying individual amino acids in the building blocks enables the structure of the assembled aggregates, and the reactions that they can catalyse, to be controlled predictably.

Tolulope O. Omosun
Ming-Chien Hsieh
David G. Lynn
Research27 Feb 2017
Nature Chemistry

Volume: 9, P: 805-809
IPv6 addressing strategy with improved secure duplicate address detection to overcome denial of service and reconnaissance attacks

Gyanendra Kumar
Anil Gankotiya
Shitharth Selvarajan
ResearchOpen Access24 Oct 2024
Scientific Reports

Volume: 14, P: 1-21
Too many ghosts in the machine

Anil Seth
Books & Arts05 Jun 2019
Nature Machine Intelligence

Volume: 1, P: 294-295
Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020

João M. Furtado
Jost B. Jonas
Rupert R. A. Bourne
ResearchOpen Access04 Jul 2024
Eye

Volume: 38, P: 2070-2082
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Opportunities and challenges for a maturing science of consciousness

Scientific research on consciousness is critical to multiple scientific, clinical, and ethical issues. The growth of the field could also be beneficial to several areas including neurology and mental health research. To achieve this goal, we need to set funding priorities carefully and address problems such as job creation and potential media misrepresentation.

Matthias Michel
Diane Beck
Masatoshi Yoshida
Comments & Opinion04 Feb 2019
Nature Human Behaviour

Volume: 3, P: 104-107
Author Correction: Perspectives on ENCODE

Federi Bronwen co Abascal
Reyes Acosta
Richard M. Myers
Amendments and CorrectionsOpen Access26 Apr 2022
Nature

Volume: 605, P: E4
Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

Konrad Pesudovs
Van Charles Lansingh
Jaimie D. Steinmetz
ResearchOpen Access09 Mar 2024
Eye

Volume: 38, P: 2156-2172
Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin

Michael M. Schartner
Robin L. Carhart-Harris
Suresh D. Muthukumaraswamy
ResearchOpen Access19 Apr 2017
Scientific Reports

Volume: 7, P: 1-12
Global estimates on the number of people blind or visually impaired by glaucoma: A meta-analysis from 2000 to 2020

Rupert R. A. Bourne
Jost B. Jonas
Jaimie D. Steinmetz
ResearchOpen Access02 Apr 2024
Eye

Volume: 38, P: 2036-2046
Perspectives on ENCODE

The authors summarize the history of the ENCODE Project, the achievements of ENCODE 1 and ENCODE 2, and how the new data generated and analysed in ENCODE 3 complement the previous phases.

Federico Abascal
Reyes Acosta
Richard M. Myers
Reviews29 Jul 2020
Nature

Volume: 583, P: 693-698
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes

Federico Abascal
Reyes Acosta
Zhiping Weng
Amendments and CorrectionsOpen Access26 Apr 2022
Nature

Volume: 605, P: E3
Publisher Correction: Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

Konrad Pesudovs
Van Charles Lansingh
Jaimie D. Steinmetz
Amendments and CorrectionsOpen Access16 Jul 2024
Eye

Volume: 38, P: 2229-2231
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Correction: Corrigendum: Differential neural mechanisms for early and late prediction error detection

Rahim Malekshahi
Anil Seth
Andrea Caria
Amendments and CorrectionsOpen Access11 Apr 2017
Scientific Reports

Volume: 7, P: 1
Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020

Julie-Anne Little
Nathan G. Congdon
Rupert Bourne
ResearchOpen Access04 Jul 2024
Eye

Volume: 38, P: 2083-2101
Differential neural mechanisms for early and late prediction error detection

Rahim Malekshahi
Anil Seth
Andrea Caria
ResearchOpen Access15 Apr 2016
Scientific Reports

Volume: 6, P: 1-14
Adults Can Be Trained to Acquire Synesthetic Experiences

Daniel Bor
Nicolas Rothen
Anil K. Seth
ResearchOpen Access18 Nov 2014
Scientific Reports

Volume: 4, P: 1-8
Transcriptome Analysis Reveals Candidate Genes involved in Blister Blight defense in Tea (Camellia sinensis (L) Kuntze)

Kuldip Jayaswall
Pallavi Mahajan
Ram Kumar Sharma
ResearchOpen Access28 Jul 2016
Scientific Reports

Volume: 6, P: 1-14
A Deep-Dream Virtual Reality Platform for Studying Altered Perceptual Phenomenology

Keisuke Suzuki
Warrick Roseboom
Anil K. Seth
ResearchOpen Access22 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
Fractionation of parietal function in bistable perception probed with concurrent TMS-EEG

Georg Schauer
Acer Chang
Ryota Kanai
ResearchOpen Access16 Aug 2016
Scientific Data

Volume: 3, P: 1-10
Malaria vaccine candidate based on Duffy-binding protein elicits strain transcending functional antibodies in a Phase I trial

Kavita Singh
Paushali Mukherjee
Chetan E. Chitnis
ResearchOpen Access28 Sept 2018
npj Vaccines

Volume: 3, P: 1-10
A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology

Lutnick et al. develop a cloud-based deep learning tool for whole slide image segmentation. The authors provide several examples of its application in renal pathology, for segmenting glomeruli, interstitial fibrosis and other features of interest.

Brendon Lutnick
David Manthey
Angela Victoria-Castro
ResearchOpen Access19 Aug 2022
Communications Medicine

Volume: 2, P: 1-15

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