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Showing 1–6 of 6 results

Advanced filters: Author: Anja Mezger Clear advanced filters

High-throughput chromatin accessibility profiling at single-cell resolution

Single-cell chromatin accessibility is a promising means to identify regulatory programs in mixtures of cells. Here the authors describe µ-ATAC-seq, a low-cost method that can generate thousands of accessibility profiles per day.

Anja Mezger
Sandy Klemm
William Greenleaf
ResearchOpen Access07 Sept 2018
Nature Communications

Volume: 9, P: 1-6
Landscape of stimulation-responsive chromatin across diverse human immune cells

Analysis of gene expression and open chromatin regions in up to 32 immune cell populations under resting and stimulated conditions identifies widespread chromatin remodeling and shared response elements between stimulated B and T cells.

Diego Calderon
Michelle L. T. Nguyen
Jonathan K. Pritchard
Research30 Sept 2019
Nature Genetics

Volume: 51, P: 1494-1505
Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

Analyzing DNA accessibility, transcriptome and protein expression in single cells uncovers cancer-regulatory programs.

Jeffrey M. Granja
Sandy Klemm
William J. Greenleaf
Research02 Dec 2019
Nature Biotechnology

Volume: 37, P: 1458-1465
Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation

Sophie Beyer
Julien Pontis
Slimane Ait-Si-Ali
ResearchOpen Access18 Oct 2016
Cell Discovery

Volume: 2, P: 1-24
Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis

Anna-Karin E Palm
Heike C Friedrich
Sandra Kleinau
Research11 May 2015
Cellular & Molecular Immunology

Volume: 12, P: 493-504
A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis

Daniel Schwarzkopf
Claudia Tanja Matthaeus-Kraemer
Gabriele Wöbker
ResearchOpen Access10 Mar 2022
Scientific Reports

Volume: 12, P: 1-13