Early T. gondii infection induces host S-phase arrest and DNA breaks, with binucleation and micronuclei formation observed by 3 h p.i., indicating genomic instability. DNA damage was MYR1-dependent and ROS-independent, compromising host DNA integrity post-infection.
- Zahady D. Velásquez
- Lisbeth Rojas-Baron
- Anja Taubert