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Showing 1–2 of 2 results
Advanced filters: Author: Anke Muth Clear advanced filters
  • The clinical use of adeno-associated virus vectors (AAVs) has been limited by the lack of transduction specificity. Here the authors show that receptor-targeted, affinity-tagged, and purified AVVs reach tumours in mouse models with high selectivity and efficiency, outperforming therapeutic antibodies.

    • Robert C. Münch
    • Anke Muth
    • Christian J. Buchholz
    Research
    Nature Communications
    Volume: 6, P: 1-9
  • Inhibitors of mitochondrial transcription that target human mitochondrial RNA polymerase provide a chemical biology tool for studying the role of mitochondrial DNA expression in a wide range of pathologies.

    • Nina A. Bonekamp
    • Bradley Peter
    • Nils-Göran Larsson
    Research
    Nature
    Volume: 588, P: 712-716