Nature Search

Cryo-EM structure of the human THIK-1 K2P K⁺ channel reveals a lower Y gate regulated by lipids and anesthetics

In this study, Rödström et al. use cryo-EM to reveal a range of structural features in THIK-1 K⁺ channel and demonstrate how these features define many functional properties of the channel, thus expanding its potential as a drug target.

Karin E. J. Rödström
Bisher Eymsh
Stephen J. Tucker
ResearchOpen Access26 Feb 2025
Nature Structural & Molecular Biology

Volume: 32, P: 1167-1174
Sequential factor delivery enables efficient workflow for universal gene editing in clinical grade iPS cells

Thomas Berger
Elitsa Borisova
Boris Greber
ResearchOpen Access12 Sept 2025
Scientific Reports

Volume: 15, P: 1-12
Averaging sleep spindle occurrence in dogs predicts learning performance better than single measures

Ivaylo Borislavov Iotchev
Vivien Reicher
Enikő Kubinyi
ResearchOpen Access31 Dec 2020
Scientific Reports

Volume: 10, P: 1-6
Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies

Michael Rassner
Tony Andreas Müller
Justus Duyster
ResearchOpen Access11 Dec 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-16
Genomic adaptations of the halophilic Dead Sea filamentous fungus Eurotium rubrum

The filamentous fungus Eurotium rubrum is one of the few organisms able to survive in the hypersaline Dead Sea. Here Kis-Papo et al. provide genomic and transcriptomic data that reveal potential cellular and metabolic mechanisms underlying adaptation to hypersaline stress in E. rubrum.

Tamar Kis-Papo
Alfons R. Weig
Eviatar Nevo
Research09 May 2014
Nature Communications

Volume: 5, P: 1-8
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF^V600 melanoma

Different adaptive mechanisms have been reported to reduce the efficacy of mutant BRAF inhibition in melanoma. Here, the authors show BRAF inhibition induces the translational regulation of metabolic genes leading to acquired therapy resistance.

Lorey K. Smith
Tiffany Parmenter
Grant A. McArthur
ResearchOpen Access01 Mar 2022
Nature Communications

Volume: 13, P: 1-21
Side bias behaviour in dogs (Canis familiaris) is influenced by task complexity

Anna Kis
Hannah Roper
József Topál
ResearchOpen Access23 Jul 2025
Scientific Reports

Volume: 15, P: 1-8
EEG Transients in the Sigma Range During non-REM Sleep Predict Learning in Dogs

Ivaylo Borislavov Iotchev
Anna Kis
Enikő Kubinyi
ResearchOpen Access11 Oct 2017
Scientific Reports

Volume: 7, P: 1-11
The interrelated effect of sleep and learning in dogs (Canis familiaris); an EEG and behavioural study

Anna Kis
Sára Szakadát
József Topál
ResearchOpen Access06 Feb 2017
Scientific Reports

Volume: 7, P: 1-6
Age-related differences and sexual dimorphism in canine sleep spindles

Ivaylo Borislavov Iotchev
Anna Kis
Enikő Kubinyi
ResearchOpen Access12 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
Electrical control of glass-like dynamics in vanadium dioxide for data storage and processing

Electronically accessible states in vanadium dioxide can be arbitrarily manipulated on short timescales and tracked beyond 10,000 s after excitation.

Mohammad Samizadeh Nikoo
Reza Soleimanzadeh
Elison Matioli
Research22 Aug 2022
Nature Electronics

Volume: 5, P: 596-603
Differences in pre-sleep activity and sleep location are associated with variability in daytime/nighttime sleep electrophysiology in the domestic dog

Nóra Bunford
Vivien Reicher
Márta Gácsi
ResearchOpen Access08 May 2018
Scientific Reports

Volume: 8, P: 1-10
Possible association between spindle frequency and reversal-learning in aged family dogs

Ivaylo Borislavov Iotchev
Dóra Szabó
Enikő Kubinyi
ResearchOpen Access16 Apr 2020
Scientific Reports

Volume: 10, P: 1-11
Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies

A method for the multimodal volumetric imaging of RNAs and proteins in intact tumour volumes and organoids enables the spatial transcriptional profiling of coding RNAs and non-coding RNAs at single-cell resolution in cancer tissues.

Nobuyuki Tanaka
Shigeaki Kanatani
Per Uhlén
Research29 Jun 2020
Nature Biomedical Engineering

Volume: 4, P: 875-888
Dog brains are sensitive to infant- and dog-directed prosody

An fMRI study on awake dogs suggests that non-primary auditory dog brain regions respond more to dog- and/or infant-directed speech than to adult-directed speech, especially when spoken by females.

Anna Gergely
Anna Gábor
Attila Andics
ResearchOpen Access18 Aug 2023
Communications Biology

Volume: 6, P: 1-9
Sensitive tumour detection and classification using plasma cell-free DNA methylomes

An immunoprecipitation-based protocol is developed to analyse DNA methylation in small quantities of circulating cell-free DNA, and can detect and classify cancers in plasma samples from several tumour types.

Shu Yi Shen
Rajat Singhania
Daniel D. De Carvalho
Research14 Nov 2018
Nature

Volume: 563, P: 579-583
Non-invasive sleep EEG measurement in hand raised wolves

Vivien Reicher
Anna Bálint
Márta Gácsi
ResearchOpen Access13 Jun 2022
Scientific Reports

Volume: 12, P: 1-11
A large-scale Boolean model of the rheumatoid arthritis fibroblast-like synoviocytes predicts drug synergies in the arthritic joint

Vidisha Singh
Aurelien Naldi
Anna Niarakis
ResearchOpen Access15 Jul 2023
npj Systems Biology and Applications

Volume: 9, P: 1-13
Event-related potentials indicate differential neural reactivity to species and valence information in vocal stimuli in sleeping dogs

Huba Eleőd
Márta Gácsi
Anna Kis
ResearchOpen Access04 Sept 2023
Scientific Reports

Volume: 13, P: 1-11
Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia

K Nebral
D Denk
S Strehl
Research20 Nov 2008
Leukemia

Volume: 23, P: 134-143
Six facial prosodic expressions caregivers similarly display to infants and dogs

Anna Gergely
Édua Koós-Hutás
József Topál
ResearchOpen Access17 Jan 2023
Scientific Reports

Volume: 13, P: 1-12
Owner-rated hyperactivity/impulsivity is associated with sleep efficiency in family dogs: a non-invasive EEG study

Cecília Carreiro
Vivien Reicher
Márta Gácsi
ResearchOpen Access23 Jan 2023
Scientific Reports

Volume: 13, P: 1-10
High-throughput, Label-Free Quantitative Proteomic Studies of the Anticancer Effects of Electrical Pulses with Turmeric Silver Nanoparticles: an in vitro Model Study

Lakshya Mittal
Ignacio G. Camarillo
Raji Sundararajan
ResearchOpen Access29 Apr 2020
Scientific Reports

Volume: 10, P: 1-18
The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms

Tibor Kovács
Viktor Billes
Tibor Vellai
ResearchOpen Access16 Feb 2017
Scientific Reports

Volume: 7, P: 1-17
The influence of voice familiarity and linguistic content on dogs’ ability to follow human voice direction

Livia Langner
Sabina Žakelj
Anna Kis
ResearchOpen Access26 Sept 2023
Scientific Reports

Volume: 13, P: 1-11
Emotional face expression recognition in problematic Internet use and excessive smartphone use: task-based fMRI study

Ákos Arató
Szilvia Anett Nagy
Gergely Darnai
ResearchOpen Access07 Jan 2023
Scientific Reports

Volume: 13, P: 1-12
Quality by design modelling to support rapid RNA vaccine production against emerging infectious diseases

Damien van de Berg
Zoltán Kis
Nilay Shah
ResearchOpen Access29 Apr 2021
npj Vaccines

Volume: 6, P: 1-10
PALB2 mutations and prostate cancer risk and survival

Dominika Wokołorczyk
Wojciech Kluźniak
Maria Małgorzata Sąsiadek
Research18 May 2021
British Journal of Cancer

Volume: 125, P: 569-575
Interhemispheric asymmetry during NREM sleep in the dog

Vivien Reicher
Anna Kis
Márta Gácsi
ResearchOpen Access22 Sept 2021
Scientific Reports

Volume: 11, P: 1-10
Developmental features of sleep electrophysiology in family dogs

Vivien Reicher
Nóra Bunford
Márta Gácsi
ResearchOpen Access23 Nov 2021
Scientific Reports

Volume: 11, P: 1-15
Maternal Genetic Ancestry and Legacy of 10^th Century AD Hungarians

Aranka Csősz
Anna Szécsényi-Nagy
Balázs Gusztáv Mende
ResearchOpen Access16 Sept 2016
Scientific Reports

Volume: 6, P: 1-13
REM versus Non-REM sleep disturbance specifically affects inter-specific emotion processing in family dogs (Canis familiaris)

Henrietta Bolló
Krisztina Kovács
Anna Kis
ResearchOpen Access26 Jun 2020
Scientific Reports

Volume: 10, P: 1-8
Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins

Norbert Bencsik
Szilvia Pusztai
Katalin Schlett
ResearchOpen Access14 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
PADAPT 1.0 – the Pannonian Dataset of Plant Traits

Judit Sonkoly
Edina Tóth
Péter Török
ResearchOpen Access25 Oct 2023
Scientific Data

Volume: 10, P: 1-8
Activity and complexes of mTOR in diffuse large B-cell lymphomas—a tissue microarray study

Anna Sebestyén
Tamás B Sticz
László Kopper
Research17 Aug 2012
Modern Pathology

Volume: 25, P: 1623-1628
Author Correction: Developmental features of sleep electrophysiology in family dogs

Vivien Reicher
Nóra Bunford
Márta Gácsi
Amendments and CorrectionsOpen Access21 Jan 2022
Scientific Reports

Volume: 12, P: 1-2
Author Correction: EEG Transients in the Sigma Range During non-REM Sleep Predict Learning in Dogs

Ivaylo Borislavov Iotchev
Anna Kis
Enikő Kubinyi
Amendments and CorrectionsOpen Access12 Apr 2018
Scientific Reports

Volume: 8, P: 1-3
Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia

K C Ray
M E Moss
A L Means
Research04 Feb 2013
Oncogene

Volume: 33, P: 823-831

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