Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Anne Freimoser-Grundschober Clear advanced filters

  • The clinical application of T cell bispecific antibodies (TCBs) is often limited by the lack of tumour-specific antigens. In this study, the authors present a strategy to increase TCB tumour-selectivity by adding an anti-CD3 moiety that can be specifically activated by tumor specific proteases in the tumor microenvironment.

    • Martina Geiger
    • Kay-Gunnar Stubenrauch
    • Christian Klein
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Binding of the PD1-IL2v immunocytokine to PD-1 and IL-2Rβγ on the same cell leads to an alternative differentiation of stem-like CD8+ T cells into better effectors rather than exhausted T cells in models of both chronic infection and cancer.

    • Laura Codarri Deak
    • Valeria Nicolini
    • Pablo Umaña
    ResearchOpen Access
    Nature
    Volume: 610, P: 161-172