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Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells

Fusobacterium nucleatum promotes colorectal cancer via its adhesin Fap2. Here, Schöpf et al. show the molecular basis for Fap2 interaction with its receptors TIGIT on immune cells and Gal-GalNAc on tumor cells using cryo-EM and integrative modeling.

Felix Schöpf
Gian L. Marongiu
Daniel Roderer
ResearchOpen Access29 Aug 2025
Nature Communications

Volume: 16, P: 1-18
Biofilm infections of endobronchial valves in COPD patients after endoscopic lung volume reduction: a pilot study with FISHseq

Eva Pappe
Ralf-Harto Hübner
Judith Kikhney
ResearchOpen Access04 Oct 2024
Scientific Reports

Volume: 14, P: 1-11
Comparing strategies for the mitigation of SARS-CoV-2 airborne infection risk in tiered auditorium venues

Sophia Mareike Geisler and Kevin Harry Lausch with colleagues study the impact of ventilation strategies on the risk of COVID transmission. They demonstrate that the use of displacement ventilation is advantageous in stopping the virus spread in tiered auditoriums.

S. Mareike Geisler
Kevin H. Lausch
Stefan Moritz
ResearchOpen Access09 Nov 2024
Communications Engineering

Volume: 3, P: 1-15
Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

Wei-Chien Andrew Kao
Helena Pětrošová
Tara J. Moriarty
ResearchOpen Access08 May 2017
Scientific Reports

Volume: 7, P: 1-13
Reaction–diffusion theory explains hypoxia and heterogeneous growth within microbial biofilms associated with chronic infections

Philip S Stewart
Tianyu Zhang
Annette Moter
ResearchOpen Access22 Jun 2016
npj Biofilms and Microbiomes

Volume: 2, P: 1-8

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Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells

Biofilm infections of endobronchial valves in COPD patients after endoscopic lung volume reduction: a pilot study with FISHseq

Comparing strategies for the mitigation of SARS-CoV-2 airborne infection risk in tiered auditorium venues

Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

Reaction–diffusion theory explains hypoxia and heterogeneous growth within microbial biofilms associated with chronic infections

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Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells

Biofilm infections of endobronchial valves in COPD patients after endoscopic lung volume reduction: a pilot study with FISHseq

Comparing strategies for the mitigation of SARS-CoV-2 airborne infection risk in tiered auditorium venues

Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

Reaction–diffusion theory explains hypoxia and heterogeneous growth within microbial biofilms associated with chronic infections

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