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Showing 1–3 of 3 results
Advanced filters: Author: Anni Kauko Clear advanced filters

  • Cancer cells can utilize the lymph node transportation network to disseminate. Here, the authors show that breast cancer can alter the lymphatic endothelial cells (LECs) in the sentinel lymph nodes and that Matrix Gla protein is upregulated in LECs, which in turn promotes cancer cell adhesion.

    • Dominik Eichin
    • Diana Lehotina
    • Sirpa Jalkanen
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • An analysis of 16 health-related quantitative traits in approximately 350,000 individuals reveals statistically significant associations between genome-wide homozygosity and four complex traits (height, lung function, cognitive ability and educational attainment); in each case increased homozygosity associates with a decreased trait value, but no evidence was seen of an influence on blood pressure, cholesterol, or ten other cardio-metabolic traits.

    • Peter K. Joshi
    • Tonu Esko
    • James F. Wilson
    Research
    Nature
    Volume: 523, P: 459-462