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Showing 1–2 of 2 results
Advanced filters: Author: Anthony M. Ciancone Clear advanced filters

  • Cryo-electron microscopy structures of apolipoprotein B100 (apoB100) in complex with the LDL receptor (LDLR) provide insight into binding interfaces and explain how mutations in apoB100 or in LDLR can give rise to familial hypercholesterolaemia.

    • Mart Reimund
    • Altaira D. Dearborn
    • Joseph Marcotrigiano
    Research
    Nature
    Volume: 638, P: 829-835

  • Sulfur-triazole exchange (SuTEx) chemistry is a tunable platform for covalent chemoproteomic probes that selectively target tyrosines, used to identify residues with enhanced nucleophilicity and monitor activation of phosphotyrosine sites.

    • Heung Sik Hahm
    • Emmanuel K. Toroitich
    • Ku-Lung Hsu
    Research
    Nature Chemical Biology
    Volume: 16, P: 150-159