The underlying cause of idiopathic dilated cardiomyopathy remains unknown, although studies have suggested a genetic component or involvement of inflammatory and autoimmune responses. Several studies have also shown that vascular dysfunction is present in idiopathic dilated cardiomyopathy. Roura and Bayes-Genis review these studies and suggest a reinterpretation of the pathophysiology in terms of the vascular changes.
- Santiago Roura
- Antoni Bayes-Genis