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Showing 1–3 of 3 results
Advanced filters: Author: Antonios Pantazis Clear advanced filters
  • CaV2.1 channels are critical for neuronal communication. Here, authors showed they undergo electrically-evoked molecular movements which (1) eventually trigger neurotransmitter release or (2) are a form of molecular memory that contributes to lifelong learning.

    • Kaiqian Wang
    • Michelle Nilsson
    • Antonios Pantazis
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13
  • The authors show that VSD-III, one of the four voltage-sensing domains of CaV1.1, has been evolutionarily assigned to serve as a sensor and transducer of skeletal muscle action potentials. The voltage-dependent motion of this sensor likely opens the ryanodine receptor causing Ca2+ release and contraction.

    • Marina Angelini
    • Nicoletta Savalli
    • Riccardo Olcese
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-10
  • Current Förster resonance energy transfer (FRET)-based fluorescence spectroscopy methods are suffering from some limitations in the field of structural biology. Here, the authors present an optical approach, distance-encoding photoinduced electron transfer (DEPET), capable of the simultaneous study of protein structure and function.

    • Antonios Pantazis
    • Karin Westerberg
    • Riccardo Olcese
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12