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Showing 1–2 of 2 results
Advanced filters: Author: Anupama Pasam Clear advanced filters

  • The heterogeneity of androgen receptor (AR) gene alterations across metastases in prostate cancer remains unresolved. Here, the authors characterise AR genomic complexity across spatially separated lethal metastases from 10 prostate cancer patients and investigate how AR alterations evolve.

    • A. M. Mahedi Hasan
    • Paolo Cremaschi
    • Gerhardt Attard
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Spatial proteomic data serve to provide cell-level location information for the extraction of biological features from tissues, but analyzing such data can be difficult. Here the authors report the development of SPIAT for data analyses and spaSim for simulation and validation of methods to help bridge the gap between the technology and its translation.

    • Yuzhou Feng
    • Tianpei Yang
    • Anna S. Trigos
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20