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Showing 1–2 of 2 results
Advanced filters: Author: Anusha Rajaraman Clear advanced filters

  • Vascular addressins control lymphocyte homing, thus regulating immunity and inflammation, but how addressin expression is patterned remains unknown. Here the authors identify composite DNA elements (NCCEs) that bind NKX2 homeodomain proteins cooperatively with COUP-TFII to define a morphogenetic code that targets transcription of mucosal vascular addressins.

    • Thanh Theresa Dinh
    • Menglan Xiang
    • Eugene C. Butcher
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • The origin and diversity of blood vascular endothelial cells (BEC) in lymphoid tissues is unclear. Here, the authors profile murine BECs from peripheral lymph nodes by single cell analysis and identify subsets of cells specialised for immune cell recruitment and vascular homeostasis.

    • Kevin Brulois
    • Anusha Rajaraman
    • Eugene C. Butcher
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15