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Showing 1–8 of 8 results
Advanced filters: Author: Anwar R Padhani Clear advanced filters
  • The process of angiogenesis is central to the development and spread of cancer. Modern imaging techniques are increasingly offering ways in which the markers of angiogenesis can be visualized. This article discusses the different imaging methods that can be used to assess angiogenesis in the prostate gland.

    • Anwar R Padhani
    • Christopher J Harvey
    • David O Cosgrove
    Reviews
    Nature Clinical Practice Urology
    Volume: 2, P: 596-607
  • Preclinical and clinical data indicate a number of potential roles of diffusion-weighted MRI in the characterization of malignancy such as determination of lesion aggressiveness and monitoring response to therapy. This Review outlines the biological basis of observations made using this technique and the authors discuss the strength of evidence for adoption of DW-MRI as a biomarker for the assessment of tumor response.

    • Daniel M Patterson
    • Anwar R Padhani
    • David J Collins
    Reviews
    Nature Clinical Practice Oncology
    Volume: 5, P: 220-233
  • Imaging biomarkers (IBs) are used extensively in drug development and cancer research, but important differences exist between IBs and biospecimen-derived biomarkers. A tailored 'roadmap' is required for the development of new IBs to be used either in clinical research or for decision-making in healthcare. In this Consensus statement, a group of experts assembled by CRUK and the EORTC present 14 key recommendations for accelerating the clinical translation of IBs.

    • James P. B. O'Connor
    • Eric O. Aboagye
    • John C. Waterton
    ReviewsOpen Access
    Nature Reviews Clinical Oncology
    Volume: 14, P: 169-186
  • In this Review, the authors analyse all the steps of the multiparametric MRI-guided prostate cancer diagnostic pathway, focusing on quality assurance systems to minimize variation in performance and discussing quality control measures to assess and mitigate poor quality throughout the process.

    • Tristan Barrett
    • Maarten de Rooij
    • Anwar R. Padhani
    Reviews
    Nature Reviews Urology
    Volume: 20, P: 9-22
  • The majority of individuals with cancer, notably those with breast or prostate cancer, will develop bone metastases. In this Primer, Coleman and colleagues discuss the epidemiology, pathophysiology and diagnosis of metastatic bone disease and highlight the specific treatment strategies to prevent disease progression and to manage skeletal morbidities.

    • Robert E. Coleman
    • Peter I. Croucher
    • Luis Costa
    Reviews
    Nature Reviews Disease Primers
    Volume: 6, P: 1-28
  • Here, the authors describe the characteristics of an ideal screening test for prostate cancer and examine why PSA fails to meet these attributes. They discuss whether an abbreviated MRI protocol could be an alternative or additional screening test for prostate cancer and explore its inherent challenges and potential solutions.

    • David Eldred-Evans
    • Henry Tam
    • Hashim U. Ahmed
    Reviews
    Nature Reviews Urology
    Volume: 17, P: 526-539