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Advanced filters: Author: April Aralar Clear advanced filters

  • Mechanisms of inefficient vaccine protection against pathobionts such as S. aureus (SA) are still unclear. Here the authors show that prior SA exposure induces non-protective CD4+ T cells, which impair IsdB vaccine protection by IL-10 secretion and IL-17A suppression, whereas IL-17A promoting adjuvant CAF01 overcomes this dilemma.

    • Irshad Ahmed Hajam
    • Chih-Ming Tsai
    • George Y. Liu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16