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Nature Neuroscience (2)

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Advanced filters: Author: Arin Pamukcu Clear advanced filters

Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons

To understand how antipsychotics modulate neural activity in the striatum, Yun et al. used in vivo imaging and found a correlation between clinical efficacy and the modulation of D1R-expressing, rather than D2R-expressing, striatal neurons in mice.

Seongsik Yun
Ben Yang
Jones G. Parker
Research13 Jul 2023
Nature Neuroscience

Volume: 26, P: 1417-1428
Cell and circuit complexity of the external globus pallidus

This Review provides a comprehensive overview of the neuronal heterogeneity, circuit architecture and functional roles of the external globus pallidus, with emphasis on how the latest data deviate from traditional views of the basal ganglia.

Connor D. Courtney
Arin Pamukcu
C. Savio Chan
Reviews19 Jun 2023
Nature Neuroscience

Volume: 26, P: 1147-1159

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Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons

Cell and circuit complexity of the external globus pallidus

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