Here the authors find that PlexinA1, a well-known Semaphorin receptor, is also a receptor for Slits. Utilizing phenotypic analysis of mouse models, they define an in vivo contribution of Plexin-Slit signaling during commissural axon guidance and demonstrate the role of the Slit C-terminal fragment in this process.
- Céline Delloye-Bourgeois
- Arnaud Jacquier
- Valérie Castellani
